Fredric P. Manfredsson, Ph.D.
Affiliations: | Translational Science & Molecular Medicine | Michigan State University, East Lansing, MI |
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Publications
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Sandoval IM, Marmion DJ, Meyers KT, et al. (2021) Gene Therapy to Modulate Alpha-Synuclein in Synucleinopathies. Journal of Parkinson's Disease |
Chatterjee D, Marmion DJ, McBride JL, et al. (2021) Enhanced CNS transduction from AAV.PHP.eB infusion into the cisterna magna of older adult rats compared to AAV9. Gene Therapy |
Sellnow RC, Steece-Collier K, Altwal F, et al. (2020) Striatal Nurr1 Facilitates the Dyskinetic State and Exacerbates Levodopa-Induced Dyskinesia in a Rat Model of Parkinson's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience |
Chu Y, Bartus RT, Manfredsson FP, et al. (2020) Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson's disease. Brain : a Journal of Neurology. 143: 960-975 |
Yelleswarapu NK, Manfredsson F, Galligan J. (2020) 351 ENTERIC NEURONAL AGGGREGATION OF α-SYNUCLEIN DISRUPTS NITRERGIC MEDIATED INHIBITORY NEUROMUSCULAR TRANMISSION Gastroenterology. 158 |
Kang SS, Liu X, Ahn EH, et al. (2019) Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus. The Journal of Clinical Investigation |
Kasanga EA, Owens CL, Cantu MA, et al. (2019) GFR-α1 expression in substantia nigra increases bilaterally following unilateral striatal GDNF in aged rats and attenuates nigral tyrosine hydroxylase loss following 6-OHDA nigrostriatal lesion. Acs Chemical Neuroscience |
Wang ZH, Xiang J, Liu X, et al. (2019) Deficiency in BDNF/TrkB Neurotrophic Activity Stimulates δ-Secretase by Upregulating C/EBPβ in Alzheimer's Disease. Cell Reports. 28: 655-669.e5 |
Romoli B, Lozada AF, Sandoval IM, et al. (2019) Neonatal Nicotine Exposure Primes Midbrain Neurons to a Dopaminergic Phenotype and Increases Adult Drug Consumption. Biological Psychiatry |
Xiang J, Wang ZH, Ahn EH, et al. (2019) Delta-secretase-cleaved Tau antagonizes TrkB neurotrophic signalings, mediating Alzheimer's disease pathologies. Proceedings of the National Academy of Sciences of the United States of America |