David M. Yurek, Ph.D.
Affiliations: | University of Kentucky, Lexington, KY |
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Publications
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| Ghosh B, Zhang C, Ziemba KS, et al. (2019) Partial Reconstruction of the Nigrostriatal Circuit along a Preformed Molecular Guidance Pathway. Molecular Therapy. Methods & Clinical Development. 14: 217-227 |
| Yurek DM, Hasselrot U, Sesenoglu-Laird O, et al. (2017) Intracerebral injections of DNA nanoparticles encoding for a therapeutic gene provide partial neuroprotection in an animal model of neurodegeneration. Nanomedicine : Nanotechnology, Biology, and Medicine |
| Yurek DM, Hasselrot U, Cass WA, et al. (2015) Age and lesion-induced increases of GDNF transgene expression in brain following intracerebral injections of DNA nanoparticles. Neuroscience. 284: 500-12 |
| Cass WA, Peters LE, Fletcher AM, et al. (2014) Calcitriol promotes augmented dopamine release in the lesioned striatum of 6-hydroxydopamine treated rats. Neurochemical Research. 39: 1467-76 |
| Zhang C, Jin Y, Ziemba KS, et al. (2013) Long distance directional growth of dopaminergic axons along pathways of netrin-1 and GDNF. Experimental Neurology. 250: 156-64 |
| Cass WA, Peters LE, Fletcher AM, et al. (2012) Evoked dopamine overflow is augmented in the striatum of calcitriol treated rats. Neurochemistry International. 60: 186-91 |
| Fletcher AM, Kowalczyk TH, Padegimas L, et al. (2011) Transgene expression in the striatum following intracerebral injections of DNA nanoparticles encoding for human glial cell line-derived neurotrophic factor. Neuroscience. 194: 220-6 |
| Yurek DM, Fletcher AM, McShane M, et al. (2011) DNA nanoparticles: detection of long-term transgene activity in brain using bioluminescence imaging. Molecular Imaging. 10: 327-39 |
| Yurek DM, Fletcher AM, Peters LE, et al. (2010) Strain difference in the up-regulation of FGF-2 protein following a neurotoxic lesion of the nigrostriatal pathway. Neurochemical Research. 35: 531-9 |
| Yurek DM, Flectcher AM, Kowalczyk TH, et al. (2009) Compacted DNA nanoparticle gene transfer of GDNF to the rat striatum enhances the survival of grafted fetal dopamine neurons. Cell Transplantation. 18: 1183-96 |