Kunhong Xiao

Affiliations: 
Department of Medicine Duke Medical School, Durham, NC, United States 
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Publications

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Han SO, Xiao K, Kim J, et al. (2012) MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors. The Journal of Cell Biology. 199: 817-30
Sarker S, Xiao K, Shenoy SK. (2011) A tale of two sites: How ubiquitination of a G protein-coupled receptor is coupled to its lysosomal trafficking from distinct receptor domains. Communicative & Integrative Biology. 4: 528-31
Nobles KN, Xiao K, Ahn S, et al. (2011) Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin. Science Signaling. 4: ra51
Hara MR, Kovacs JJ, Whalen EJ, et al. (2011) A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1. Nature. 477: 349-53
Xiao K, Shenoy SK. (2011) β2-adrenergic receptor lysosomal trafficking is regulated by ubiquitination of lysyl residues in two distinct receptor domains Journal of Biological Chemistry. 286: 12785-12795
Shukla AK, Kim J, Ahn S, et al. (2010) Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4. The Journal of Biological Chemistry. 285: 30115-25
Shenoy SK, Modi AS, Shukla AK, et al. (2009) Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2. Proceedings of the National Academy of Sciences of the United States of America. 106: 6650-5
Shenoy SK, Xiao K, Venkataramanan V, et al. (2008) Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor. The Journal of Biological Chemistry. 283: 22166-76
Shenoy SK, Barak LS, Xiao K, et al. (2007) Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation. The Journal of Biological Chemistry. 282: 29549-62
Xiao K, McClatchy DB, Shukla AK, et al. (2007) Functional specialization of beta-arrestin interactions revealed by proteomic analysis. Proceedings of the National Academy of Sciences of the United States of America. 104: 12011-6
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