S. Michael Owens

Affiliations: 
Pharmacology and Toxicology University of Arkansas for Medical Sciences, United States 
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Children

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Kelly A. Byrnes-Blake grad student 2001 UAMS
Alessandra Milesi-Halle grad student 2005 UAMS
Jonathan J. Hubbard grad student 2008 UAMS
Michael D. Hambuchen grad student 2013 UAMS

Collaborators

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William E. Fantegrossi collaborator 2015- UAMS
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Publications

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McClenahan SJ, Gunnell MG, Owens SM, et al. (2020) Active vaccination reduces reinforcing effects of MDPV in male Sprague-Dawley rats trained to self-administer cocaine. Psychopharmacology
Hay CE, Ewing LE, Hambuchen MD, et al. (2020) The development and characterization of an scFv-Fc fusion based gene therapy to reduce the psychostimulant effects of methamphetamine abuse. The Journal of Pharmacology and Experimental Therapeutics
Keller CM, Spence AL, Stevens MW, et al. (2019) Effects of a methamphetamine vaccine, IXT-v100, on methamphetamine-related behaviors. Psychopharmacology
McClenahan SJ, Kormos CM, Gunnell M, et al. (2019) Design, synthesis and biological evaluation of a bi-specific vaccine against α-pyrrolidinovalerophenone (α-PVP) and 3,4-methylenedioxypyrovalerone (MDPV) in rats. Vaccine
Stevens MW, Rüedi-Bettschen D, Gunnell MG, et al. (2019) Antibody production and pharmacokinetics of METH in rats following vaccination with the METH vaccine, IXT-v100, adjuvanted with GLA-SE. Drug and Alcohol Dependence. 204: 107484
Hambuchen MD, Berquist MD, Simecka CM, et al. (2019) Effect of Bile Duct Ligation-induced Liver Dysfunction on Methamphetamine Pharmacokinetics and Locomotor Activity in Rats. Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society For Pharmaceutical Sciences, Societe Canadienne Des Sciences Pharmaceutiques. 22: 301-312
Griffin BA, Caperton CO, Russell LN, et al. (2019) exposure to norbuprenorphine, a major metabolite of buprenorphine, induces fetal opioid dependence and leads to neonatal opioid withdrawal syndrome. The Journal of Pharmacology and Experimental Therapeutics
McClenahan SJ, Hambuchen MD, Simecka CM, et al. (2019) Cardiovascular effects of 3,4-methylenedioxypyrovalerone (MDPV) in male and female Sprague-Dawley rats. Drug and Alcohol Dependence. 195: 140-147
Hay CE, Gonzalez GA, Ewing LE, et al. (2018) Development and testing of AAV-delivered single-chain variable fragments for the treatment of methamphetamine abuse. Plos One. 13: e0200060
Hambuchen MD, Hendrickson HP, Gunnell MG, et al. (2017) The pharmacokinetics of racemic MDPV and its (R) and (S) enantiomers in female and male rats. Drug and Alcohol Dependence. 179: 347-354
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