Jean Bennett, MD PhD
Affiliations: | Ophthalmology | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Ocular Gene TherapyWebsite:
http://www.med.upenn.edu/apps/faculty/index.php/g327/p11214Google:
"Jean Bennett"Bio:
https://www.med.upenn.edu/apps/faculty/index.php/g20000440/p11214
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137328/
DOI: 10.1089/hum.2014.2529
Parents
Sign in to add mentor| Daniel Mazia | grad student | 1976-1980 | UC Berkeley (Neurotree) | |
| (Fusion of sea urchin eggs.) | ||||
| Roger A Pedersen | post-doc | 1980-1982 | UCSF | |
| French Anderson | post-doc | 1983 | NIH | |
| Leon Rosenberg | post-doc | 1986-1987 | Yale (Cell Biology Tree) | |
| John D. Gearhart | post-doc | 1987-1989 | Johns Hopkins Medical School (Neurotree) | |
Children
Sign in to add trainee| Matthew Canver | research assistant | 2008-2009 | Penn |
| Daniel J. Bennett | research assistant | 2012-2012 | Penn |
| Nicoletta Commins | research assistant | 2012-2012 | Penn |
| Giulia Casal | research assistant | 2014-2015 | Penn |
| Luk H. Vandenberghe | grad student | Penn | |
| Christopher Greer | grad student | 2017- | Penn |
| Abha R. Gupta | grad student | 2000 | Penn |
| Kathryn C. Behling | grad student | 2000-2004 | Penn |
| Nicholas W. Keiser | grad student | 2006 | Penn |
| Defne A. Amado | grad student | 2007-2010 | Penn |
| Aaron Black | grad student | 2010-2014 | Penn |
| Theodore Drivas | grad student | 2011-2014 | Penn |
| Adam Wojno | grad student | 2012-2015 | Penn |
| Laura Bryant | grad student | 2012-2017 | Penn |
| Thu Duong | grad student | 2012-2018 | Penn |
| Scott Dooley | grad student | 2013-2018 | Penn |
| Devin McDougald | grad student | 2013-2018 | Penn |
| Lindsey Weed | grad student | 2015-2019 | Penn |
| Leon Morales | grad student | 2016-2020 | Penn |
| Tonia S. Rex | post-doc | Penn | |
| Vibha Anand Jawa | post-doc | 1999-2003 | Penn |
| Enrico M. Surace | post-doc | 2000-2003 | Penn |
| Akiko Kuroki | post-doc | 2002-2003 | Penn |
| Fong-Qi Liang | post-doc | 1999-2004 | Penn |
| Nadine Dejneka | post-doc | 1998-2005 | Penn |
| Gareth Lima | post-doc | 2008-2008 | Penn |
| Gabriela Silva | post-doc | 2006-2009 | Penn |
| Therese Cronin | post-doc | 2009-2011 | Penn |
| Pyroja Sulaiman | post-doc | 2009-2011 | Penn |
| Jessica I. Morgan | post-doc | 2009-2012 | Penn (Neurotree) |
| Rachel M. Huckfeldt | post-doc | 2013-2014 | Penn (Neurotree) |
| Matthew Sochor | post-doc | 2014-2014 | Penn |
| Jason Mills | post-doc | 2016-2016 | Penn |
| Pavitra S. Ramachandran | post-doc | 2014-2017 | Penn (Neurotree) |
| Ji Yun Song | post-doc | 2015-2017 | Penn |
| Katherine Palozola | post-doc | 2017-2019 | Penn |
| Katherine E. Uyhazi | post-doc | 2017-2019 | Penn (FlyTree) |
| Lanfranco Leo | post-doc | 2016-2021 | Penn |
| Maria Vicky Luna-Velez | research scientist | Penn | |
| Jeffrey Bedrosian | research scientist | 2004-2005 | Penn |
| Wei Wong | research scientist | 2004-2005 | Penn |
| Vivian Lee | research scientist | 2005-2005 | Penn |
| Daniel C. Chung | research scientist | 2003-2014 | Penn |
| Keirnan Willett | research scientist | 2018-2019 | Penn |
| Vidyullatha Vasireddy | research scientist | 2013-2020 | Penn |
BETA: Related publications
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Publications
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| Chaqour B, Duong TT, Yue J, et al. (2024) AAV2 vector optimization for retinal ganglion cell-targeted delivery of therapeutic genes. Gene Therapy |
| Afanasyeva TAV, Athanasiou D, Perdigao PRL, et al. (2023) CRISPR-Cas9 correction of a nonsense mutation in rescues lebercilin expression and localization in human retinal organoids. Molecular Therapy. Methods & Clinical Development. 29: 522-531 |
| Bennett J. (2022) Overview of Retinal Gene Therapy: Current Status and Future Challenges. Cold Spring Harbor Perspectives in Medicine |
| Bennett J, Maguire AM. (2022) Lessons Learned from the Development of the First FDA-Approved Gene Therapy Drug, Voretigene Neparvovec-rzyl. Cold Spring Harbor Perspectives in Medicine |
| Isgrig K, Ishibashi Y, Lee HJ, et al. (2022) AAV8BP2 and AAV8 transduce the mammalian cochlear lateral wall and endolymphatic sac with high efficiency. Molecular Therapy. Methods & Clinical Development. 26: 371-383 |
| Aleman TS, Huckfeldt RM, Serrano LW, et al. (2022) AAV2-hCHM Subretinal Delivery to the Macula in Choroideremia: Two Year Interim Results of an Ongoing Phase I/II Gene Therapy Trial. Ophthalmology |
| Nikonov S, Aravand P, Lyubarsky A, et al. (2022) Restoration of Vision and Retinal Responses After Adeno-Associated Virus-Mediated Optogenetic Therapy in Blind Dogs. Translational Vision Science & Technology. 11: 24 |
| Morgan JIW, Jiang YY, Vergilio GK, et al. (2022) Short-term Assessment of Subfoveal Injection of Adeno-Associated Virus-Mediated hCHM Gene Augmentation in Choroideremia Using Adaptive Optics Ophthalmoscopy. Jama Ophthalmology |
| Argyriou C, Polosa A, Song JY, et al. (2021) AAV-mediated gene augmentation improves visual function in the PEX1-Gly844Asp mouse model for mild Zellweger spectrum disorder. Molecular Therapy. Methods & Clinical Development. 23: 225-240 |
| Maguire AM, Russell S, Chung DC, et al. (2021) Durability of Voretigene Neparvovec for Biallelic RPE65-Mediated Inherited Retinal Disease: Phase 3 Results at 3 Years and 4 Years. Ophthalmology |