Yuchen Chen
Affiliations: | 2012-2017 | MCIBS201 | Pennsylvania State University, State College, PA, United States |
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Publications
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He X, Wang X, Wang H, et al. (2023) NeuroD1 Regulated Endothelial Gene Expression to Modulate Transduction of AAV-PHP.eB and Recovery Progress after Ischemic Stroke. Aging and Disease |
Tang Y, Wu Q, Gao M, et al. (2021) Restoration of Visual Function and Cortical Connectivity After Ischemic Injury Through NeuroD1-Mediated Gene Therapy. Frontiers in Cell and Developmental Biology. 9: 720078 |
Zhang L, Lei Z, Guo Z, et al. (2020) Development of Neuroregenerative Gene Therapy to Reverse Glial Scar Tissue Back to Neuron-Enriched Tissue. Frontiers in Cellular Neuroscience. 14: 594170 |
Wu Z, Parry M, Hou XY, et al. (2020) Gene therapy conversion of striatal astrocytes into GABAergic neurons in mouse models of Huntington's disease. Nature Communications. 11: 1105 |
Chubykin A, Tang Y, Wu Q, et al. (2020) Synaptic circuit restoration and functional recovery in the mouse visual cortex after ischemic injury and direct in vivo reprogramming of astrocytes into neurons The Faseb Journal. 34: 1-1 |
Chen YC, Ma NX, Pei ZF, et al. (2019) A NeuroD1 AAV-Based Gene Therapy for Functional Brain Repair after Ischemic Injury through In Vivo Astrocyte-to-Neuron Conversion. Molecular Therapy : the Journal of the American Society of Gene Therapy |
Ju TC, Chen HM, Chen YC, et al. (2014) AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease. Biochimica Et Biophysica Acta. 1842: 1668-80 |
Hsiao HY, Chiu FL, Chen CM, et al. (2014) Inhibition of soluble tumor necrosis factor is therapeutic in Huntington's disease. Human Molecular Genetics. 23: 4328-44 |
Guo Z, Zhang L, Wu Z, et al. (2014) In vivo direct reprogramming of reactive glial cells into functional neurons after brain injury and in an Alzheimer's disease model. Cell Stem Cell. 14: 188-202 |
Hsiao HY, Chen YC, Chen HM, et al. (2013) A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease. Human Molecular Genetics. 22: 1826-42 |