Gaynor A Smith

Affiliations: 
Cardiff University, Cardiff, Wales, United Kingdom 
Area:
Drosophila, Parkinson's disease, Huntington's disease, mitochondria
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"Gaynor Smith"
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Parents

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Stephen B. Dunnett grad student 2007-2020
Ole Isacson post-doc 2011-2014
Marc R. Freeman post-doc 2014-2017
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Publications

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Precious SV, Smith GA, Heuer A, et al. (2020) Dopaminergic Progenitors Derived From Epiblast Stem Cells Function Similarly to Primary VM-Derived Progenitors When Transplanted Into a Parkinson's Disease Model. Frontiers in Neuroscience. 14: 312
Breger LS, Kienle K, Smith GA, et al. (2016) Influence of chronic L-DOPA treatment on immune response following allogeneic and xenogeneic graft in a rat model of Parkinson's disease. Brain, Behavior, and Immunity
Smith GA, Jansson J, Rocha EM, et al. (2015) Fibroblast Biomarkers of Sporadic Parkinson's Disease and LRRK2 Kinase Inhibition. Molecular Neurobiology
Rocha EM, Smith GA, Park E, et al. (2015) Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons. Neurobiology of Disease
Rocha EM, Smith GA, Park E, et al. (2015) Chronic pharmacological glucocerebrosidase inhibition induces α-synuclein aggregation, microglial and complement activation and synaptic protein changes in mice. Antioxidants & Redox Signaling
Rocha EM, Smith GA, Park E, et al. (2015) Progressive decline of glucocerebrosidase in aging and Parkinson's disease. Annals of Clinical and Translational Neurology. 2: 433-8
Smith GA, Rocha EM, Rooney T, et al. (2015) A Nurr1 agonist causes neuroprotection in a Parkinson's disease lesion model primed with the toll-like receptor 3 dsRNA inflammatory stimulant poly(I:C). Plos One. 10: e0121072
Hallett PJ, Deleidi M, Astradsson A, et al. (2015) Successful function of autologous iPSC-derived dopamine neurons following transplantation in a non-human primate model of Parkinson's disease. Cell Stem Cell. 16: 269-74
Lewis EA, Smith GA. (2015) Using Drosophila models of Huntington's disease as a translatable tool Journal of Neuroscience Methods
McLean JR, Smith GA, Rocha EM, et al. (2014) ALS-associated peripherin spliced transcripts form distinct protein inclusions that are neuroprotective against oxidative stress. Experimental Neurology. 261: 217-29
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