Shiva N. Kompella, PhD

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2010-2013 School of Medical Sciences RMIT University, Melbourne, Victoria, Australia 
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Cuny H, Yu R, Tae HS, et al. (2017) α-Conotoxins active at α3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition. British Journal of Pharmacology
Cuny H, Kompella SN, Tae HS, et al. (2016) Key Structural Determinants in the Agonist Binding Loops of Human β2 and β4 Nicotinic Acetylcholine Receptor Subunits Contribute to α3β4 Subtype Selectivity of α-Conotoxins. The Journal of Biological Chemistry
Kompella SN, Cuny H, Hung A, et al. (2015) Molecular Basis for Differential Sensitivity of α-Conotoxin RegIIA at Rat and Human Neuronal Nicotinic Acetylcholine Receptors. Molecular Pharmacology. 88: 993-1001
Xu S, Zhang T, Kompella SN, et al. (2015) Conotoxin αD-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors. Scientific Reports. 5: 14261
Kompella SN, Hung A, Clark RJ, et al. (2015) Alanine scan of α-conotoxin RegIIA reveals a selective α3β4 nicotinic acetylcholine receptor antagonist. The Journal of Biological Chemistry. 290: 1039-48
Chhabra S, Belgi A, Bartels P, et al. (2014) Dicarba analogues of α-conotoxin RgIA. Structure, stability, and activity at potential pain targets. Journal of Medicinal Chemistry. 57: 9933-44
Inserra MC, Kompella SN, Vetter I, et al. (2013) Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors. Biochemical Pharmacology. 86: 791-9
van Lierop BJ, Robinson SD, Kompella SN, et al. (2013) Dicarba α-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors. Acs Chemical Biology. 8: 1815-21
Yu R, Kompella SN, Adams DJ, et al. (2013) Determination of the α-conotoxin Vc1.1 binding site on the α9α10 nicotinic acetylcholine receptor. Journal of Medicinal Chemistry. 56: 3557-67
Franco A, Kompella SN, Akondi KB, et al. (2012) RegIIA: an α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs. Biochemical Pharmacology. 83: 419-26
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