Simon T. Nevin

Affiliations: 
2004-2009 School of Biomedical Sciences University of Queensland, Saint Lucia, Queensland, Australia 
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Hopping G, Wang CI, Hogg RC, et al. (2014) Hydrophobic residues at position 10 of α-conotoxin PnIA influence subtype selectivity between α7 and α3β2 neuronal nicotinic acetylcholine receptors. Biochemical Pharmacology. 91: 534-42
de Araujo AD, Callaghan B, Nevin ST, et al. (2011) Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Ed. in English). 50: 6527-9
Daly NL, Callaghan B, Clark RJ, et al. (2011) Structure and activity of α-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABAB receptor-coupled N-type calcium channels Journal of Biological Chemistry. 286: 10233-10237
Lovelace ES, Gunasekera S, Alvarmo C, et al. (2011) Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization Antioxidants and Redox Signaling. 14: 87-95
Clark RJ, Jensen J, Nevin ST, et al. (2010) The engineering of an orally active conotoxin for the treatment of neuropathic pain Angewandte Chemie - International Edition. 49: 6545-6548
Muttenthaler M, Nevin ST, Grishin AA, et al. (2010) Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists. Journal of the American Chemical Society. 132: 3514-22
Halai R, Clark RJ, Nevin ST, et al. (2009) Scanning mutagenesis of α-conotoxin Vc1.1 reveals residues crucial for activity at the α9α10 nicotinic acetylcholine receptor Journal of Biological Chemistry. 284: 20275-20284
Millard EL, Nevin ST, Loughnan ML, et al. (2009) Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues. The Journal of Biological Chemistry. 284: 4944-51
Samson AL, Nevin ST, Croucher D, et al. (2008) Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function. Journal of Neurochemistry. 107: 1091-101
Jin AH, Daly NL, Nevin ST, et al. (2008) Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function. Journal of Medicinal Chemistry. 51: 5575-84
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