Sandra Hewett, Ph.D.

Biology Syracuse University, Syracuse, NY, United States 
Interplay between Excitotoxicity and Inflammation
"Sandra Hewett"
Mean distance: 106866 (cluster 11)
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Sears SMS, Hewett JA, Hewett SJ. (2019) Decreased epileptogenesis in mice lacking the System x transporter occurs in association with a reduction in AMPA receptor subunit GluA1. Epilepsia Open. 4: 133-143
Chowdhury T, Allen MF, Thorn TL, et al. (2018) Interleukin-1β Protects Neurons against Oxidant-Induced Injury via the Promotion of Astrocyte Glutathione Production. Antioxidants (Basel, Switzerland). 7
Kanzler MA, Van Dyke AM, He Y, et al. (2018) Mice lacking L-12/15-lipoxygenase show increased mortality during kindling despite demonstrating resistance to epileptogenesis. Epilepsia Open. 3: 255-263
He Y, Akumuo RC, Yang Y, et al. (2017) Mice deficient in L-12/15 lipoxygenase show increased vulnerability to 3-nitropropionic acid neurotoxicity. Neuroscience Letters
Hewett SJ, Shi J, Gong Y, et al. (2016) Spontaneous Glutamatergic Synaptic Activity Regulates Constitutive COX-2 Expression in Neurons: Opposing roles for the transcription factors CREB and Sp1. The Journal of Biological Chemistry
Shi J, He Y, Hewett SJ, et al. (2015) Interleukin 1β regulation of the system xc- substrate-specific subunit, xCT, in primary mouse astrocytes involves the RNA-binding protein HuR. The Journal of Biological Chemistry
Thorn TL, He Y, Jackman NA, et al. (2015) A Cytotoxic, Co-operative Interaction Between Energy Deprivation and Glutamate Release From System xc- Mediates Aglycemic Neuronal Cell Death. Asn Neuro. 7
He Y, Jackman NA, Thorn TL, et al. (2015) Interleukin-1β protects astrocytes against oxidant-induced injury via an NF-κB-Dependent upregulation of glutathione synthesis. Glia. 63: 1568-80
Jackman NA, Melchior SE, Hewett JA, et al. (2012) Non-cell autonomous influence of the astrocyte system xc- on hypoglycaemic neuronal cell death. Asn Neuro. 4
Hewett JA, Hewett SJ. (2012) Induction of nitric oxide synthase-2 expression and measurement of nitric oxide production in enriched primary cortical astrocyte cultures. Methods in Molecular Biology (Clifton, N.J.). 814: 251-63
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