Andrew E. Arrant, PhD
Affiliations: | Neurology | University of Alabama, Birmingham, Birmingham, AL, United States |
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"Andrew Arrant"Mean distance: 15.15 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| Cynthia Moreton Kuhn | grad student | 2007-2012 | Duke | |
| (Why Does Risk-Taking Peak During Adolescence?: Contribution of Neurochemical and Circuit-Level Function to Lower Serotonin-Mediated Behavioral Inhibition in Adolescents.) | ||||
| Erik Roberson | post-doc | 2013-2019 | UAB | |
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Publications
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| Kashyap SN, Fox SN, Wilson KI, et al. (2024) Carboxy-terminal blockade of sortilin binding enhances progranulin gene therapy, a potential treatment for frontotemporal dementia. Biorxiv : the Preprint Server For Biology |
| Cook AK, Greathouse KM, Manuel PN, et al. (2024) Dendritic spine head diameter is reduced in the prefrontal cortex of progranulin haploinsufficient mice. Molecular Brain. 17: 33 |
| Kaplelach AK, Fox SN, Cook AK, et al. (2023) Regulation of extracellular progranulin in medial prefrontal cortex. Neurobiology of Disease. 188: 106326 |
| Kurnellas M, Mitra A, Schwabe T, et al. (2023) Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia. Journal of Translational Medicine. 21: 387 |
| Davis SE, Cook AK, Hall JA, et al. (2023) Patients with sporadic FTLD exhibit similar increases in lysosomal proteins and storage material as patients with FTD due to GRN mutations. Acta Neuropathologica Communications. 11: 70 |
| Davis SE, Roth JR, Aljabi Q, et al. (2021) Delivering progranulin to neuronal lysosomes protects against excitotoxicity. The Journal of Biological Chemistry. 100993 |
| Arrant AE, Davis SE, Vollmer RM, et al. (2020) Elevated levels of extracellular vesicles in progranulin-deficient mice and FTD-GRN Patients. Annals of Clinical and Translational Neurology |
| Arrant AE, Roth JR, Boyle NR, et al. (2019) Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations. Acta Neuropathologica Communications. 7: 218 |
| Stoyka LE, Arrant AE, Thrasher DR, et al. (2019) Behavioral defects associated with amygdala and cortical dysfunction in mice with seeded α-synuclein inclusions. Neurobiology of Disease. 104708 |
| Arrant AE, Boyle NR, Roth JR, et al. (2019) P1-186: IMPAIRED β-GLUCOCEREBROSIDASE ACTIVITY AND PROCESSING IN FRONTOTEMPORAL DEMENTIA DUE TO PROGRANULIN MUTATIONS Alzheimers & Dementia. 15 |