Spyridon Theofilopoulos
Affiliations: | 2007-2015 | MBB | Karolinska Institute, Stockholm, Sweden |
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| Hennegan J, Bryant AH, Griffiths L, et al. (2023) Inhibition of 7α,26-dihydroxycholesterol biosynthesis promotes midbrain dopaminergic neuron development. Iscience. 27: 108670 |
| Griffiths WJ, Abdel-Khalik J, Moore SF, et al. (2021) The Cerebrospinal Fluid Profile of Cholesterol Metabolites in Parkinson's Disease and Their Association With Disease State and Clinical Features. Frontiers in Aging Neuroscience. 13: 685594 |
| Meljon A, Crick PJ, Yutuc E, et al. (2019) Mining for Oxysterols in Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5. Biomolecules. 9 |
| Theofilopoulos S, Abreu de Oliveira WA, Yang S, et al. (2019) 24(),25-Epoxycholesterol and () overexpression promote midbrain dopaminergic neurogenesis . The Journal of Biological Chemistry |
| Griffiths WJ, Crick PJ, Meljon A, et al. (2018) Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1-/- mouse brain and plasma. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids |
| Gyllborg D, Ahmed M, Toledo EM, et al. (2018) The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation. Stem Cell Reports |
| Hedlund E, Belnoue L, Theofilopoulos S, et al. (2016) Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors. Scientific Reports. 6: 26448 |
| Theofilopoulos S, Arenas E. (2015) Liver X receptors and cholesterol metabolism: role in ventral midbrain development and neurodegeneration. F1000prime Reports. 7: 37 |
| Theofilopoulos S, Griffiths WJ, Crick PJ, et al. (2014) Cholestenoic acids regulate motor neuron survival via liver X receptors. The Journal of Clinical Investigation. 124: 4829-42 |
| Theofilopoulos S, Wang Y, Kitambi SS, et al. (2013) Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis. Nature Chemical Biology. 9: 126-33 |