Stefan Prokop

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Microglia, Neurodegeneration, Alzheimer, Parkinsons
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Parents

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Christian Haass grad student 2002-2005
Virginia Man-Yee Lee post-doc 2015-
John Q. Trojanowski post-doc 2015-
Adriano Aguzzi post-doc 2006-2008
Frank Heppner post-doc 2008-2015

Collaborators

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Todd Golde collaborator
Kelly R Miller collaborator
Tony Wyss-Coray collaborator
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Publications

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Trejo-Lopez JA, Sorrentino ZA, Riffe CJ, et al. (2020) Novel Monoclonal Antibodies Targeting the RRM2 domain of Human TDP-43 Protein. Neuroscience Letters. 135353
Xia Y, Prokop S, Gorion KM, et al. (2020) Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer's disease and other tauopathies. Acta Neuropathologica Communications. 8: 88
Drost N, Houtman J, Cseresnyés Z, et al. (2020) The Amyloid-beta rich CNS environment alters myeloid cell functionality independent of their origin. Scientific Reports. 10: 7152
Lloyd GM, Trejo-Lopez JA, Xia Y, et al. (2020) Prominent amyloid plaque pathology and cerebral amyloid angiopathy in APP V717I (London) carrier - phenotypic variability in autosomal dominant Alzheimer's disease. Acta Neuropathologica Communications. 8: 31
Trejo-Lopez JA, Sorrentino ZA, Riffe CJ, et al. (2020) Generation and Characterization of Novel Monoclonal Antibodies Targeting p62/sequestosome-1 Across Human Neurodegenerative Diseases. Journal of Neuropathology and Experimental Neurology
Eede P, Obst J, Benke E, et al. (2020) Interleukin-12/23 deficiency differentially affects pathology in male and female Alzheimer's disease-like mice. Embo Reports. e48530
Prokop S, Lee VMY, Trojanowski JQ. (2019) Neuroimmune interactions in Alzheimer's disease-New frontier with old challenges? Progress in Molecular Biology and Translational Science. 168: 183-201
Sacino AN, Prokop S, Walsh MA, et al. (2019) Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology. Acta Neuropathologica Communications. 7: 158
Prokop S, Miller KR, Labra SR, et al. (2019) Impact of TREM2 risk variants on brain region-specific immune activation and plaque microenvironment in Alzheimer's disease patient brain samples. Acta Neuropathologica
Wagner LK, Gilling KE, Schormann E, et al. (2017) Immunoproteasome deficiency alters microglial cytokine response and improves cognitive deficits in Alzheimer's disease-like APPPS1 mice. Acta Neuropathologica Communications. 5: 52
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