Steven J. Gray
Affiliations: | 2008-2018 | Gene Therapy Center | University of North Carolina, Chapel Hill, Chapel Hill, NC |
2017- | Neurology and Pediatrics | University of Texas Southwestern Medical Center, Dallas, TX, United States |
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Cross-listing: Cell & Gene Therapy Tree
Parents
Sign in to add mentorEllen Fanning | grad student | 2000-2006 | Vanderbilt (Chemistry Tree) |
Jude Samulski | post-doc | 2006-2008 | UNC Chapel Hill (Cell & Gene Therapy Tree) |
Children
Sign in to add traineeIrvin Thomas Garza | grad student | 2023- | UT Southwestern |
Charles Shyng | post-doc | 2016-2018 | UNC Chapel Hill |
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Publications
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Presa M, Bailey RM, Ray S, et al. (2025) Preclinical use of a clinically-relevant scAAV9/SUMF1 vector for the treatment of multiple sulfatase deficiency. Communications Medicine. 5: 29 |
Bharucha-Goebel DX, Todd JJ, Saade D, et al. (2024) Intrathecal Gene Therapy for Giant Axonal Neuropathy. The New England Journal of Medicine. 390: 1092-1104 |
Gumusgoz E, Kasiri S, Verma M, et al. (2023) CSTB gene replacement improves neuroinflammation, neurodegeneration and ataxia in murine type 1 progressive myoclonus epilepsy. Gene Therapy |
Vyas M, Deschenes NM, Osmon KJL, et al. (2023) Efficacy of Adeno-Associated Virus Serotype 9-Mediated Gene Therapy for AB-Variant GM2 Gangliosidosis. International Journal of Molecular Sciences. 24 |
Ling Q, Herstine JA, Bradbury A, et al. (2023) AAV-based in vivo gene therapy for neurological disorders. Nature Reviews. Drug Discovery |
Casy W, Garza IT, Chen X, et al. (2023) SMRT Sequencing Enables High-Throughput Identification of Novel AAVs from Capsid Shuffling and Directed Evolution. Genes. 14 |
Wong H, Hooper AW, Kang HR, et al. (2023) CNS-dominant human FMRP isoform rescues seizures, fear, and sleep abnormalities in Fmr1-KO mice. Jci Insight. 8 |
Chen X, Lim DA, Lawlor MW, et al. (2023) Biodistribution of adeno-associated virus gene therapy following CSF-directed administration. Human Gene Therapy |
Ling Q, Rioux M, Hu Y, et al. (2021) Adeno-associated viral vector serotype 9-based gene replacement therapy for -related Leigh syndrome. Molecular Therapy. Methods & Clinical Development. 23: 158-168 |
Judson MC, Shyng C, Simon JM, et al. (2021) Dual-isoform hUBE3A gene transfer improves behavioral and seizure outcomes in Angelman syndrome model mice. Jci Insight. 6 |