William C. Hahn, M.D., Ph.D.
Affiliations: | Molecular and Cellular Oncology, Medical Oncology | Harvard Medical School, Dana Farber Cancer Institute, Broad Institute of Harvard and MIT, |
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EGFR , RNAiWebsite:
http://research4.dfci.harvard.edu/hahnlab//index.htmlGoogle:
"William Hahn"Mean distance: 26716.5
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Schaefer A, Hodge RG, Zhang H, et al. (2023) RHOA drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling. Science Signaling. 16: eadg5289 |
Krill-Burger JM, Dempster JM, Borah AA, et al. (2023) Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal. Genome Biology. 24: 192 |
de Matos Simoes R, Shirasaki R, Downey-Kopyscinski SL, et al. (2023) Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias. Nature Cancer. 4: 754-773 |
Perurena N, Lock R, Davis RA, et al. (2023) USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities. Cell Reports. Medicine. 101007 |
Sharifnia T, Wawer MJ, Goodale A, et al. (2023) Mapping the landscape of genetic dependencies in chordoma. Nature Communications. 14: 1933 |
Bala P, Rennhack JP, Aitymbayev D, et al. (2023) Aberrant cell state plasticity mediated by developmental reprogramming precedes colorectal cancer initiation. Science Advances. 9: eadf0927 |
Cervia LD, Shibue T, Borah AA, et al. (2022) A ubiquitination cascade regulating the integrated stress response and survival in carcinomas. Cancer Discovery |
Schröfelbauer B, Kimes PK, Hauke P, et al. (2022) Discovery of antibodies and cognate surface targets for ovarian cancer by surface profiling. Proceedings of the National Academy of Sciences of the United States of America. 120: e2206751120 |
Hagel KR, Arafeh R, Gang S, et al. (2022) Systematic interrogation of tumor cell resistance to CAR T cell therapy in pancreatic cancer. Cancer Research |
Williams HL, Dias Costa A, Zhang J, et al. (2022) Spatially-resolved single-cell assessment of pancreatic cancer expression subtypes reveals co-expressor phenotypes and extensive intra-tumoral heterogeneity. Cancer Research |