W Davis Parker

Affiliations: 
Neurology University of Virginia School of Medicine, Charlottesville, VA, United States 
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Publications

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Parker WD, Parks JK, Swerdlow RH. (2008) Complex I deficiency in Parkinson's disease frontal cortex. Brain Research. 1189: 215-8
McAllister J, Ghosh S, Berry D, et al. (2008) Effects of memantine on mitochondrial function. Biochemical Pharmacology. 75: 956-64
Smigrodzki R, Goertzel B, Pennachin C, et al. (2005) Genetic algorithm for analysis of mutations in Parkinson's disease. Artificial Intelligence in Medicine. 35: 227-41
Parker WD, Parks JK. (2005) Mitochondrial ND5 mutations in idiopathic Parkinson's disease. Biochemical and Biophysical Research Communications. 326: 667-9
Smigrodzki R, Parks J, Parker WD. (2004) High frequency of mitochondrial complex I mutations in Parkinson's disease and aging. Neurobiology of Aging. 25: 1273-81
Trimmer PA, Borland MK, Keeney PM, et al. (2004) Parkinson's disease transgenic mitochondrial cybrids generate Lewy inclusion bodies. Journal of Neurochemistry. 88: 800-12
Trimmer PA, Keeney PM, Borland MK, et al. (2004) Mitochondrial abnormalities in cybrid cell models of sporadic Alzheimer's disease worsen with passage in culture. Neurobiology of Disease. 15: 29-39
Swerdlow RH, Parks JK, Cassarino DS, et al. (2001) Biochemical analysis of cybrids expressing mitochondrial DNA from Contursi kindred Parkinson's subjects. Experimental Neurology. 169: 479-85
Parks JK, Smith TS, Trimmer PA, et al. (2001) Neurotoxic Abeta peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro. Journal of Neurochemistry. 76: 1050-6
Albers DS, Swerdlow RH, Manfredi G, et al. (2001) Further evidence for mitochondrial dysfunction in progressive supranuclear palsy. Experimental Neurology. 168: 196-8
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