Jean-Philippe Loeffler

Affiliations: 
University of Strasbourg, Strasbourg, Grand Est, France 
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"Jean-Philippe Loeffler"
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Bouscary A, Quessada C, René F, et al. (2020) Drug repositioning in neurodegeneration: An overview of the use of ambroxol in neurodegenerative diseases. European Journal of Pharmacology. 884: 173446
Henriques A, Croixmarie V, Bouscary A, et al. (2017) Sphingolipid Metabolism Is Dysregulated at Transcriptomic and Metabolic Levels in the Spinal Cord of an Animal Model of Amyotrophic Lateral Sclerosis. Frontiers in Molecular Neuroscience. 10: 433
Henriques A, Huebecker M, Blasco H, et al. (2017) Inhibition of β-Glucocerebrosidase Activity Preserves Motor Unit Integrity in a Mouse Model of Amyotrophic Lateral Sclerosis. Scientific Reports. 7: 5235
Muller S, Brun S, René F, et al. (2017) Autophagy in neuroinflammatory diseases. Autoimmunity Reviews. 16: 856-874
Vernay A, Therreau L, Blot B, et al. (2016) A transgenic mouse expressing CHMP2Bintron5 mutant in neurons develops histological and behavioural features of amyotrophic lateral sclerosis and frontotemporal dementia. Human Molecular Genetics. 25: 3341-3360
Neidl R, Schneider A, Bousiges O, et al. (2016) Late-Life Environmental Enrichment Induces Acetylation Events and Nuclear Factor κB-Dependent Regulations in the Hippocampus of Aged Rats Showing Improved Plasticity and Learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 4351-61
Loeffler JP, Picchiarelli G, Dupuis L, et al. (2016) The Role of Skeletal Muscle in Amyotrophic Lateral Sclerosis. Brain Pathology (Zurich, Switzerland). 26: 227-36
Henriques A, Croixmarie V, Priestman DA, et al. (2015) Amyotrophic lateral sclerosis and denervation alter sphingolipids and up-regulate glucosylceramide synthase. Human Molecular Genetics. 24: 7390-405
Palamiuc L, Schlagowski A, Ngo ST, et al. (2015) A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosis. Embo Molecular Medicine. 7: 526-46
Schmitt F, Hussain G, Dupuis L, et al. (2014) A plural role for lipids in motor neuron diseases: energy, signaling and structure. Frontiers in Cellular Neuroscience. 8: 25
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