Saikat Chowdhury, Ph.D.

2006-2012 Biochemistry and Molecular Biology The Pennsylvania State University-Eberly College of Science  
 2013-2018 Integrative Structural and Computational Biology The Scripps Research Institute, California, USA 
 2018-2021 Biochemistry and Cell Biology Stony Brook University, Stony Brook, NY, United States 
Structural Biology
"Saikat Chowdhury"
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Yang S, Tang Y, Liu Y, et al. (2022) Arf GTPase activates the WAVE regulatory complex through a distinct binding site. Science Advances. 8: eadd1412
Ding B, Yang S, Schaks M, et al. (2022) Structures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase. Nature Communications. 13: 5444
Ding B, Narvaez-Ortiz HY, Singh Y, et al. (2022) Structure of Arp2/3 complex at a branched actin filament junction resolved by single-particle cryo-electron microscopy. Proceedings of the National Academy of Sciences of the United States of America. 119: e2202723119
Anzelon TA, Chowdhury S, Hughes SM, et al. (2021) Structural basis for piRNA targeting. Nature
Basanta B, Chowdhury S, Lander GC, et al. (2020) A guided approach for subtomogram averaging of challenging macromolecular assemblies. Journal of Structural Biology: X. 4: 100041
Shaaban M, Chowdhury S, Nolen BJ. (2020) Cryo-EM reveals the transition of Arp2/3 complex from inactive to nucleation-competent state. Nature Structural & Molecular Biology
Chowdhury S, Shaaban MH, Nolen B. (2020) Cryo-EM Reveals Actin Filament Nucleation by Activated Arp2/3 Complex Biophysical Journal. 118
Rollins MF, Chowdhury S, Carter J, et al. (2019) Structure Reveals a Mechanism of CRISPR-RNA-Guided Nuclease Recruitment and Anti-CRISPR Viral Mimicry. Molecular Cell
Otomo T, Chowdhury S, Lander GC. (2018) The rod-shaped ATG2A-WIPI4 complex tethers membranes in vitro. Contact (Thousand Oaks (Ventura County, Calif.)). 1
Chowdhury S, Otomo C, Leitner A, et al. (2018) Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex. Proceedings of the National Academy of Sciences of the United States of America
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