Alice D. Lam, M.D. Ph.D.

Affiliations: 
Neurology Harvard University, Cambridge, MA, United States 
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"Alice Lam"
Mean distance: 16.11 (cluster 6)
 
SNBCP

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Edward L. Stuenkel grad student 2010 University of Michigan
 (Investigations into the dynamic molecular mechanisms that govern the final stages of neurotransmitter release.)
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Publications

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Ben-Simon Y, Rodenas-Ruano A, Alviña K, et al. (2015) A Combined Optogenetic-Knockdown Strategy Reveals a Major Role of Tomosyn in Mossy Fiber Synaptic Plasticity. Cell Reports. 12: 396-404
Ben-Simon Y, Rodenas-Ruano A, Alviña K, et al. (2015) A Combined Optogenetic-Knockdown Strategy Reveals a Major Role of Tomosyn in Mossy Fiber Synaptic Plasticity Cell Reports. 12: 396-404
Bielopolski N, Lam AD, Bar-On D, et al. (2014) Differential interaction of tomosyn with syntaxin and SNAP25 depends on domains in the WD40 β-propeller core and determines its inhibitory activity. The Journal of Biological Chemistry. 289: 17087-99
Williams AL, Bielopolski N, Meroz D, et al. (2011) Structural and functional analysis of tomosyn identifies domains important in exocytotic regulation. The Journal of Biological Chemistry. 286: 14542-53
Lam AD, Ismail S, Wu R, et al. (2010) Mapping dynamic protein interactions to insulin secretory granule behavior with TIRF-FRET. Biophysical Journal. 99: 1311-20
Lam AD, Tryoen-Toth P, Tsai B, et al. (2008) SNARE-catalyzed fusion events are regulated by Syntaxin1A-lipid interactions. Molecular Biology of the Cell. 19: 485-97
Gladycheva SE, Lam AD, Liu J, et al. (2007) Receptor-mediated regulation of tomosyn-syntaxin 1A interactions in bovine adrenal chromaffin cells. The Journal of Biological Chemistry. 282: 22887-99
D'Andrea-Merrins M, Chang L, Lam AD, et al. (2007) Munc18c interaction with syntaxin 4 monomers and SNARE complex intermediates in GLUT4 vesicle trafficking. The Journal of Biological Chemistry. 282: 16553-66
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