Matt J. Merrins, Ph.D.

Affiliations: 
Pharmacology University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Beta cell metabolism, oscillations
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"Matt Merrins"
Mean distance: 16.11 (cluster 6)
 
SNBCP
Cross-listing: Chemistry Tree

Parents

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Edward L. Stuenkel grad student 2008 University of Michigan
 (Rab27a and Munc18 as molecular determinants of SNARE-mediated vesicle docking, priming, and fusion in glucose regulatory tissues.)
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Publications

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de Souza AH, Tang J, Yadev AK, et al. (2020) Intra-islet GLP-1, but not CCK, is necessary for β-cell function in mouse and human islets. Scientific Reports. 10: 2823
Douros JD, Niu J, Sdao S, et al. (2019) Temporal plasticity of insulin and incretin secretion and insulin sensitivity following sleeve gastrectomy contribute to sustained improvements in glucose control. Molecular Metabolism
Douros JD, Niu J, Sdao SM, et al. (2019) Sleeve gastrectomy rapidly enhances islet function independently of body weight. Jci Insight
Capozzi ME, Svendsen B, Encisco SE, et al. (2019) β-Cell tone is defined by proglucagon peptides through cyclic AMP signaling. Jci Insight
De Leon ER, Brinkman JA, Fenske RJ, et al. (2018) Age-Dependent Protection of Insulin Secretion in Diet Induced Obese Mice. Scientific Reports. 8: 17814
Hennings TG, Chopra DG, DeLeon ER, et al. (2018) In vivo Deletion of Beta Cell Drp1 Impairs Insulin Secretion without Affecting Islet Oxygen Consumption. Endocrinology
LEWANDOWSKI SL, MERRINS MJ. (2018) Glucose Oxidation Depletes Cytosolic Citrate and Glutamate in the Amplifying Pathways of Insulin Secretion Diabetes. 67: 2152-P
SDAO S, POUDEL C, MORTENSEN KM, et al. (2018) Cdk2-Dependent Activation of ß-Cell Metabolism Is Eclipsed by Its Inhibitory Effect on Plasma Membrane Excitability and Insulin Secretion Diabetes. 67: 2140-P
Neuman JC, Schaid MD, Brill AL, et al. (2017) Enriching Islet Phospholipids with Eicosapentaenoic Acid Reduces Prostaglandin E2 Signaling and Enhances Diabetic β-cell Function. Diabetes
Kim SY, Lee JH, Merrins MJ, et al. (2017) Loss of Cyclin Dependent Kinase 2 in the Pancreas Links Primary β-cell Dysfunction to Progressive Depletion of β-cell Mass and Diabetes. The Journal of Biological Chemistry
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