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Donald F. Steiner, M.D.

Affiliations: 
Biochemistry & Molecular Biology University of Chicago, Chicago, IL 
Website:
http://bmb.uchospitals.edu/Faculty_and_Research/01_Faculty/01_Faculty_Alphabetically.php?faculty_id=60
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"Donald F. Steiner"
Bio:

http://www.nasonline.org/member-directory/members/50103.html
http://dx.doi.org/10.1074/jbc.X111.244764

Mean distance: 18.1 (cluster 11)
 
SNBCP
Cross-listing: Chemistry Tree

Parents

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Herbert S. Anker research assistant 1956 Chicago (Chemistry Tree)
 (The production of precipitating antibodies by spleen in vitro)

Children

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Jeffrey M. Zigman grad student 1990-1994 Chicago
Howard S. Tager post-doc 1973 Chicago (Chemistry Tree)
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Publications

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Menting JG, Yang Y, Chan SJ, et al. (2014) Protective hinge in insulin opens to enable its receptor engagement. Proceedings of the National Academy of Sciences of the United States of America. 111: E3395-404
Park SY, Ludwig MZ, Tamarina NA, et al. (2014) Genetic complexity in a Drosophila model of diabetes-associated misfolded human proinsulin. Genetics. 196: 539-55
Kanatsuna N, Taneera J, Vaziri-Sani F, et al. (2013) Autoimmunity against INS-IGF2 protein expressed in human pancreatic islets. The Journal of Biological Chemistry. 288: 29013-23
Menting JG, Whittaker J, Margetts MB, et al. (2013) How insulin engages its primary binding site on the insulin receptor. Nature. 493: 241-5
Cyr NE, Stuart RC, Zhu X, et al. (2012) Biosynthesis of proTRH-derived peptides in prohormone convertase 1 and 2 knockout mice. Peptides. 35: 42-8
Refaie S, Gagnon S, Gagnon H, et al. (2012) Disruption of proprotein convertase 1/3 (PC1/3) expression in mice causes innate immune defects and uncontrolled cytokine secretion. The Journal of Biological Chemistry. 287: 14703-17
Steiner DF. (2011) On the discovery of precursor processing. Methods in Molecular Biology (Clifton, N.J.). 768: 3-11
Steiner DF. (2011) Adventures with insulin in the islets of Langerhans. The Journal of Biological Chemistry. 286: 17399-421
Stein J, Milewski WM, Hara M, et al. (2011) GSK-3 inactivation or depletion promotes β-cell replication via down regulation of the CDK inhibitor, p27 (Kip1). Islets. 3: 21-34
Vlacich G, Nawijn MC, Webb GC, et al. (2010) Pim3 negatively regulates glucose-stimulated insulin secretion. Islets. 2: 308-17
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