Jeffrey Milbrandt, MD, PhD

Genetics Washington University School of Medicine, St. Louis, MO, United States 
Axonal degeneration, peripheral neuropathy, Myelination, Schwann cell metabolism
"Jeffrey Milbrandt"

Present: James S. McDonnell Professor and Chair, Department of Genetics, Washington University School of Medicine
MD, Washington University, St. Louis
PhD, biochemistry, University of Virginia,
Resident, pathology, University of Virginia

Mean distance: 16.15 (cluster 11)
Cross-listing: GenetiTree - Chemistry Tree

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Brazill JM, Shen IR, Craft CS, et al. (2024) Sarm1 knockout prevents type 1 diabetic bone disease in females independent of neuropathy. Jci Insight
DeVault L, Mateusiak C, Palucki J, et al. (2023) The response of Dual-Leucine Zipper Kinase (DLK) to nocodazole: evidence for a homeostatic cytoskeletal repair mechanism. Biorxiv : the Preprint Server For Biology
Klontz E, Obi JO, Wang Y, et al. (2023) The structure of NAD consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations. The Journal of Biological Chemistry. 105290
Dingwall CB, Strickland A, Yum SW, et al. (2022) Macrophage depletion blocks congenital SARM1-dependent neuropathy. The Journal of Clinical Investigation
Yamada Y, Strickland A, Sasaki Y, et al. (2022) A SARM1/mitochondrial feedback loop drives neuropathogenesis in a Charcot-Marie-Tooth disease type 2A rat model. The Journal of Clinical Investigation
Yenkin AL, Bramley JC, Kremitzki CL, et al. (2022) Pooled image-base screening of mitochondria with microraft isolation distinguishes pathogenic mitofusin 2 mutations. Communications Biology. 5: 1128
Manik MK, Shi Y, Li S, et al. (2022) Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling. Science (New York, N.Y.). eadc8969
Zaydman MA, Little AA, Haro F, et al. (2022) Defining hierarchical protein interaction networks from spectral analysis of bacterial proteomes. Elife. 11
Krus KL, Strickland A, Yamada Y, et al. (2022) Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy. Cell Reports. 39: 111001
Weagley JS, Zaydman M, Venkatesh S, et al. (2022) Products of gut microbial Toll/interleukin-1 receptor domain NADase activities in gnotobiotic mice and Bangladeshi children with malnutrition. Cell Reports. 39: 110738
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