Lauren Mifflin

Harvard Medical School, Boston, MA, United States 
"Lauren Mifflin"
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Julie Blendy research assistant 2009-2011 Penn
Junying Yuan grad student 2016- Harvard Medical School
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Li W, Shan B, Zou C, et al. (2022) Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response. Cell Research
Wang H, Qi W, Zou C, et al. (2021) NEK1-mediated retromer trafficking promotes blood-brain barrier integrity by regulating glucose metabolism and RIPK1 activation. Nature Communications. 12: 4826
Mifflin L, Hu Z, Dufort C, et al. (2021) A RIPK1-regulated inflammatory microglial state in amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 118
Zou C, Mifflin L, Hu Z, et al. (2020) Reduction of mNAT1/hNAT2 Contributes to Cerebral Endothelial Necroptosis and Aβ Accumulation in Alzheimer's Disease. Cell Reports. 33: 108447
Najafov A, Luu HS, Mookhtiar AK, et al. (2020) RIPK1 Promotes Energy Sensing by the mTORC1 Pathway. Molecular Cell
Xu D, Zhao H, Jin M, et al. (2020) Modulating TRADD to restore cellular homeostasis and inhibit apoptosis. Nature
Mifflin L, Ofengeim D, Yuan J. (2020) Receptor-interacting protein kinase 1 (RIPK1) as a therapeutic target. Nature Reviews. Drug Discovery
Xu D, Jin T, Zhu H, et al. (2018) TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging. Cell
Ofengeim D, Mazzitelli S, Ito Y, et al. (2017) RIPK1 mediates a disease-associated microglial response in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America
Ecke LE, Cleck JN, White P, et al. (2011) CREB-mediated alterations in the amygdala transcriptome: coordinated regulation of immune response genes following cocaine. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 14: 1111-26
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