Sumit Prakash, Ph.D.

Affiliations: 
2007 Biochemistry and Molecular Biology Northwestern University, Evanston, IL 
 2016 Chemistry and Chemical Biology University of California, San Francisco, San Francisco, CA 
Area:
Cancer Signaling
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"Sumit Prakash"
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Parents

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Andreas T. Matouschek grad student 2006 (Chemistry Tree)
Jack Taunton post-doc 2016 (Chemistry Tree)
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Publications

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Bashore C, Prakash S, Johnson MC, et al. (2022) Targeted degradation via direct 26S proteasome recruitment. Nature Chemical Biology. 19: 55-63
Cockram PE, Kist M, Prakash S, et al. (2021) Ubiquitination in the regulation of inflammatory cell death and cancer. Cell Death and Differentiation. 28: 591-605
Wertz I, Kategaya L, Lello PD, et al. (2018) Abstract SY23-03: Development and mechanistic characterization of USP7 deubiquitinase inhibitors Cancer Research. 78
Kategaya L, Di Lello P, Rougé L, et al. (2017) USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature
Okrut J, Prakash S, Wu Q, et al. (2015) Allosteric N-WASP activation by an inter-SH3 domain linker in Nck. Proceedings of the National Academy of Sciences of the United States of America
Fishbain S, Prakash S, Herrig A, et al. (2011) Rad23 escapes degradation because it lacks a proteasome initiation region. Nature Communications. 2: 192
Inobe T, Fishbain S, Prakash S, et al. (2011) Defining the geometry of the two-component proteasome degron. Nature Chemical Biology. 7: 161-7
Inobe T, Prakash S, Fishbain S, et al. (2010) 1P034 1YA0915 Defining the geometry of the two-component proteasome degron(Protein:Structure & Function,Early Research in Biophysics Award Candidate Presentations,Early Research in Biophysics Award,The 48th Annual Meeting of the Biophysical Society of Japan) Seibutsu Butsuri. 50: S24-S25
Koodathingal P, Jaffe NE, Kraut DA, et al. (2009) ATP-dependent proteases differ substantially in their ability to unfold globular proteins. The Journal of Biological Chemistry. 284: 18674-84
Prakash S, Inobe T, Hatch AJ, et al. (2009) Substrate selection by the proteasome during degradation of protein complexes. Nature Chemical Biology. 5: 29-36
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