Chris Bakal

Institute of Cancer Research, London, UK 
cell morphogenesis, systems biology, mechanotransduction, cell imaging
"Chris Bakal"
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Barker CG, Petsalaki E, Giudice G, et al. (2022) Identification of phenotype-specific networks from paired gene expression-cell shape imaging data. Genome Research. 32: 750-765
Hégarat N, Crncec A, Suarez Peredo Rodriguez MF, et al. (2020) Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B. The Embo Journal. e104419
Stojic L, Lun ATL, Mascalchi P, et al. (2020) A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division. Nature Communications. 11: 1851
Müller PM, Rademacher J, Bagshaw RD, et al. (2020) Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions. Nature Cell Biology
Peñalosa-Ruiz G, Bousgouni V, Gerlach JP, et al. (2019) WDR5, BRCA1, and BARD1 Co-regulate the DNA Damage Response and Modulate the Mesenchymal-to-Epithelial Transition during Early Reprogramming. Stem Cell Reports
Hansel CS, Crowder SW, Cooper S, et al. (2019) Nanoneedle-Mediated Stimulation of Cell Mechanotransduction Machinery. Acs Nano
Spill F, Bakal C, Mak M. (2018) Mechanical and Systems Biology of Cancer. Computational and Structural Biotechnology Journal. 16: 237-245
Heldt FS, Barr AR, Cooper S, et al. (2018) A comprehensive model for the proliferation-quiescence decision in response to endogenous DNA damage in human cells. Proceedings of the National Academy of Sciences of the United States of America
Sanchez-Alvarez M, Bakal C. (2018) PERK links the clock and protein stress in cancer. Nature Cell Biology. 20: 4-5
Sanchez-Alvarez M, Del Pozo MA, Bakal C. (2017) AKT-mTOR signaling modulates the dynamics of IRE1 RNAse activity by regulating ER-mitochondria contacts. Scientific Reports. 7: 16497
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