Lauren M Slosky
Affiliations: | Duke University, Durham, NC |
Area:
pain, addiction, GPCRsGoogle:
"Lauren Slosky"Mean distance: (not calculated yet)
Parents
Sign in to add mentorTodd W. Vanderah | grad student | 2011-2015 | University of Arizona |
Marc Caron | post-doc | Duke |
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Publications
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Singhal SM, Zell V, Faget L, et al. (2023) Neurotensin receptor 1-biased ligand attenuates neurotensin-mediated excitation of ventral tegmental area dopamine neurons and dopamine release in the nucleus accumbens. Neuropharmacology. 109544 |
Krumm BE, DiBerto JF, Olsen RHJ, et al. (2023) Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator. Biochemistry |
Slosky LM, Pires A, Bai Y, et al. (2022) Establishment of multi-stage intravenous self-administration paradigms in mice. Scientific Reports. 12: 21422 |
Hornburg KJ, Slosky LM, Cofer G, et al. (2022) Prenatal Heroin Exposure Alters Brain Morphology and Connectivity in Adolescent Mice. Nmr in Biomedicine. e4842 |
Slosky LM, Caron MG, Barak LS. (2021) Biased Allosteric Modulators: New Frontiers in GPCR Drug Discovery. Trends in Pharmacological Sciences |
Slosky LM, Bai Y, Toth K, et al. (2020) β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors. Cell |
Toth K, Nagi K, Slosky LM, et al. (2019) Encoding the β-Arrestin Trafficking Fate of Ghrelin Receptor GHSR1a: C-Tail-Independent Molecular Determinants in GPCRs. Acs Pharmacology & Translational Science. 2: 230-246 |
Pinkerton AB, Peddibhotla S, Yamamoto F, et al. (2019) Discovery of b-Arrestin Biased, Orally Bioavailable and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators. Journal of Medicinal Chemistry |
Toth K, Slosky LM, Pack TF, et al. (2017) Ghrelin receptor antagonism of hyperlocomotion in cocaine-sensitized mice requires βarrestin-2. Synapse (New York, N.Y.) |
Grenald SA, Doyle TM, Zhang H, et al. (2017) Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation. Pain |