Lauren M Slosky

Duke University, Durham, NC 
pain, addiction, GPCRs
"Lauren Slosky"
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Slosky LM, Caron MG, Barak LS. (2021) Biased Allosteric Modulators: New Frontiers in GPCR Drug Discovery. Trends in Pharmacological Sciences
Slosky LM, Bai Y, Toth K, et al. (2020) β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors. Cell
Toth K, Nagi K, Slosky LM, et al. (2019) Encoding the β-Arrestin Trafficking Fate of Ghrelin Receptor GHSR1a: C-Tail-Independent Molecular Determinants in GPCRs. Acs Pharmacology & Translational Science. 2: 230-246
Pinkerton AB, Peddibhotla S, Yamamoto F, et al. (2019) Discovery of b-Arrestin Biased, Orally Bioavailable and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators. Journal of Medicinal Chemistry
Toth K, Slosky LM, Pack TF, et al. (2017) Ghrelin receptor antagonism of hyperlocomotion in cocaine-sensitized mice requires βarrestin-2. Synapse (New York, N.Y.)
Grenald SA, Doyle TM, Zhang H, et al. (2017) Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation. Pain
Forte BL, Slosky LM, Zhang H, et al. (2016) Angiotensin-(1-7)/Mas Receptor as an Antinociceptive Agent in Cancer-Induced Bone Pain. Pain
Slosky LM, BassiriRad NM, Symons AM, et al. (2016) The Cystine/Glutamate Antiporter System xc- Drives Breast Tumor Cell Glutamate Release and Cancer-Induced Bone Pain. Pain
Slosky LM, Largent-Milnes TM, Vanderah TW. (2015) Use of Animal Models in Understanding Cancer-induced Bone Pain. Cancer Growth and Metastasis. 8: 47-62
Slosky LM, Vanderah TW. (2015) Therapeutic potential of peroxynitrite decomposition catalysts: a patent review. Expert Opinion On Therapeutic Patents. 25: 443-66
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