Hong Yu

Janssen R&D 
"Hong Yu"
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David Bredt research scientist 2004- Eli Lilly & Co
 (and Janssen R&D)
Eric Schaeffer research scientist 1994-1997 Pfizer Global R&D
Phil Skolnick research scientist 1997-2001 Eli Lilly & Co
Beth J Hoffman research scientist 2001-2004 Eli Lilly & Co
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Kweon HJ, Gu S, Witham E, et al. (2020) NACHO Engages N-Glycosylation ER Chaperone Pathways for α7 Nicotinic Receptor Assembly. Cell Reports. 32: 108025
Dhara M, Matta JA, Lei M, et al. (2020) Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology. Nature Communications. 11: 2799
Dawe GB, Yu H, Gu S, et al. (2019) α7 nicotinic acetylcholine receptor upregulation by anti-apoptotic Bcl-2 proteins. Nature Communications. 10: 2746
Kato AS, Burris KD, Gardinier KM, et al. (2016) Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism. Nature Medicine
Gardinier KM, Gernert DL, Porter WJ, et al. (2016) The Discovery of The First α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent Upon Transmembrane AMPA Receptor Regulatory Protein (TARP) Gamma-8. Journal of Medicinal Chemistry
Erlenhardt N, Yu H, Abiraman K, et al. (2016) Porcupine Controls Hippocampal AMPAR Levels, Composition, and Synaptic Transmission. Cell Reports
Gill MB, Kato AS, Roberts MF, et al. (2011) Cornichon-2 modulates AMPA receptor-transmembrane AMPA receptor regulatory protein assembly to dictate gating and pharmacology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6928-38
Schober DA, Gill MB, Yu H, et al. (2011) Transmembrane AMPA receptor regulatory proteins and cornichon-2 allosterically regulate AMPA receptor antagonists and potentiators. The Journal of Biological Chemistry. 286: 13134-42
Kato AS, Gill MB, Ho MT, et al. (2010) Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins. Neuron. 68: 1082-96
Kato AS, Gill MB, Yu H, et al. (2010) TARPs differentially decorate AMPA receptors to specify neuropharmacology. Trends in Neurosciences. 33: 241-8
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