Hong Yu
Affiliations: | Janssen R&D |
Area:
AMPA, NMDA, nAchRGoogle:
"Hong Yu"Mean distance: (not calculated yet)
Parents
Sign in to add mentorDavid Bredt | research scientist | 2004- | Eli Lilly & Co | |
(and Janssen R&D) | ||||
Eric Schaeffer | research scientist | 1994-1997 | Pfizer Global R&D | |
Phil Skolnick | research scientist | 1997-2001 | Eli Lilly & Co | |
Beth J Hoffman | research scientist | 2001-2004 | Eli Lilly & Co |
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Publications
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Kweon HJ, Gu S, Witham E, et al. (2020) NACHO Engages N-Glycosylation ER Chaperone Pathways for α7 Nicotinic Receptor Assembly. Cell Reports. 32: 108025 |
Dhara M, Matta JA, Lei M, et al. (2020) Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology. Nature Communications. 11: 2799 |
Dawe GB, Yu H, Gu S, et al. (2019) α7 nicotinic acetylcholine receptor upregulation by anti-apoptotic Bcl-2 proteins. Nature Communications. 10: 2746 |
Kato AS, Burris KD, Gardinier KM, et al. (2016) Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism. Nature Medicine |
Gardinier KM, Gernert DL, Porter WJ, et al. (2016) The Discovery of The First α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent Upon Transmembrane AMPA Receptor Regulatory Protein (TARP) Gamma-8. Journal of Medicinal Chemistry |
Erlenhardt N, Yu H, Abiraman K, et al. (2016) Porcupine Controls Hippocampal AMPAR Levels, Composition, and Synaptic Transmission. Cell Reports |
Gill MB, Kato AS, Roberts MF, et al. (2011) Cornichon-2 modulates AMPA receptor-transmembrane AMPA receptor regulatory protein assembly to dictate gating and pharmacology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6928-38 |
Schober DA, Gill MB, Yu H, et al. (2011) Transmembrane AMPA receptor regulatory proteins and cornichon-2 allosterically regulate AMPA receptor antagonists and potentiators. The Journal of Biological Chemistry. 286: 13134-42 |
Kato AS, Gill MB, Ho MT, et al. (2010) Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins. Neuron. 68: 1082-96 |
Kato AS, Gill MB, Yu H, et al. (2010) TARPs differentially decorate AMPA receptors to specify neuropharmacology. Trends in Neurosciences. 33: 241-8 |