Wayne Michael Patrick

University of Victoria, Victoria, British Columbia, Canada 
"Wayne Patrick"
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Brewster JL, Pachl P, McKellar JLO, et al. (2021) Structures and kinetics of Thermotoga maritima MetY reveal new insights into the predominant sulfurylation enzyme of bacterial methionine biosynthesis. The Journal of Biological Chemistry. 100797
Vickers CJ, Fraga D, Patrick WM. (2021) Quantifying the taxonomic bias in enzymology. Protein Science : a Publication of the Protein Society
Hall KR, Robins KJ, Williams EM, et al. (2020) Intracellular complexities of acquiring a new enzymatic function revealed by mass-randomisation of active site residues. Elife. 9
Söderholm A, Newton MS, Patrick WM, et al. (2020) Structure and kinetics of indole-3-glycerol phosphate synthase from - decarboxylation is not essential for indole formation. The Journal of Biological Chemistry
Wardell SJT, Rehman A, Martin LW, et al. (2019) A large-scale whole-genome comparison shows that experimental evolution in response to antibiotics predicts changes in naturally evolved clinical . Antimicrobial Agents and Chemotherapy
Rehman A, Patrick WM, Lamont IL. (2019) Mechanisms of ciprofloxacin resistance in Pseudomonas aeruginosa: new approaches to an old problem. Journal of Medical Microbiology. 68: 1-10
Newton MS, Arcus VL, Gerth ML, et al. (2017) Enzyme evolution: innovation is easy, optimization is complicated. Current Opinion in Structural Biology. 48: 110-116
Maddock DJ, Gerth ML, Patrick WM. (2017) An engineered glycerol dehydratase with improved activity for the conversion of meso-2,3-butanediol to butanone. Biotechnology Journal
Ferla MP, Brewster JL, Hall KR, et al. (2017) Primordial-like enzymes from bacteria with reduced genomes. Molecular Microbiology
Newton MS, Guo X, Söderholm A, et al. (2017) Structural and functional innovations in the real-time evolution of new (βα)8 barrel enzymes. Proceedings of the National Academy of Sciences of the United States of America
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