Theodore L. Roth

Affiliations: 
Stanford University, Palo Alto, CA 
 UCSF School of Medicine 
 National Institutes of Health-NINDS 
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"Theodore Roth"
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Roth TL, Lu J, McClellan A, et al. (2025) Non-viral intron knock-ins for targeted gene integration into human T cells and for T-cell selection. Nature Biomedical Engineering
Lareau CA, Yin Y, Maurer K, et al. (2023) Latent human herpesvirus 6 is reactivated in CAR T cells. Nature
Blaeschke F, Chen YY, Apathy R, et al. (2023) Modular pooled discovery of synthetic knockin sequences to program durable cell therapies. Cell. 186: 4216-4234.e33
Shy BR, Vykunta VS, Ha A, et al. (2022) High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails. Nature Biotechnology
Carnevale J, Shifrut E, Kale N, et al. (2022) RASA2 ablation in T cells boosts antigen sensitivity and long-term function. Nature
Hiatt J, Hultquist JF, McGregor MJ, et al. (2022) A functional map of HIV-host interactions in primary human T cells. Nature Communications. 13: 1752
DeSilva D, Ferguson L, Chin GH, et al. (2021) Robust T cell activation requires an eIF3-driven burst in T cell receptor translation. Elife. 10
Hiatt J, Cavero DA, McGregor MJ, et al. (2021) Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins. Cell Reports. 35: 109105
Lee Y, Bogdanoff D, Wang Y, et al. (2021) XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment. Science Advances. 7
Muller YD, Nguyen DP, Ferreira LMR, et al. (2021) The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28. Frontiers in Immunology. 12: 639818
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