Morgan A Coburn

Affiliations: 
University of California, Irvine, Irvine, CA 
Area:
Microglia and Alzheimer's
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"Morgan Coburn"
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Publications

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Evans KT, Blake K, Longworth A, et al. (2023) Microglia promote anti-tumour immunity and suppress breast cancer brain metastasis. Nature Cell Biology
McQuade A, Kang YJ, Hasselmann J, et al. (2023) Author Correction: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease. Nature Communications. 14: 1194
Kiani Shabestari S, Morabito S, Danhash EP, et al. (2022) Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice. Cell Reports. 39: 110961
Claes C, England WE, Danhash EP, et al. (2022) The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association
McQuade A, Kang YJ, Hasselmann J, et al. (2020) Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease. Nature Communications. 11: 5370
Davtyan H, Hovakimyan A, Kiani Shabestari S, et al. (2019) Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice. Alzheimer's Research & Therapy. 11: 107
Hovakimyan A, Antonyan T, Shabestari SK, et al. (2019) A MultiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: therapeutic efficacy in PS19 mice. Scientific Reports. 9: 15455
Hasselmann J, Coburn MA, England W, et al. (2019) Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo. Neuron
McQuade A, Coburn M, Tu CH, et al. (2018) Development and validation of a simplified method to generate human microglia from pluripotent stem cells. Molecular Neurodegeneration. 13: 67
Church JS, Tijerina PB, Emerson FJ, et al. (2017) Perinatal exposure to concentrated ambient particulates results in autism-like behavioral deficits in adult mice. Neurotoxicology
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