Laetitia Francelle

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Neurosciences
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"Laetitia Francelle"
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Parents

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Emmanuel Brouillet grad student 2011-2014
Vance Lemmon post-doc 2019-2019
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Publications

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Francelle L, Mazzulli JR. (2022) Neuroinflammation in Gaucher disease, neuronal ceroid lipofuscinosis, and commonalities with Parkinson's disease. Brain Research. 1780: 147798
Francelle L, Outeiro TF, Rappold GA. (2020) Inhibition of HDAC6 activity protects dopaminergic neurons from alpha-synuclein toxicity. Scientific Reports. 10: 6064
Galvan L, Francelle L, Gaillard MC, et al. (2018) The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin. Brain : a Journal of Neurology
de Oliveira RM, Vicente Miranda H, Francelle L, et al. (2017) The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease. Plos Biology. 15: e2000374
Francelle L, Lotz C, Outeiro T, et al. (2017) Contribution of Neuroepigenetics to Huntington's Disease. Frontiers in Human Neuroscience. 11: 17
Pardo J, Abba M, Lacunza E, et al. (2017) Identification of a conserved gene signature associated with an exacerbated inflammatory environment in the hippocampus of aging rats. Hippocampus
Pépin J, Francelle L, Carrillo-de Sauvage MA, et al. (2016) In vivo imaging of brain glutamate defects in a knock-in mouse model of Huntington's disease. Neuroimage. 139: 53-64
Flament J, Pépin J, Francelle L, et al. (2016) B40 In vivo imaging of brain glutamate defects in a knock-in mouse model of huntington’s disease Journal of Neurology, Neurosurgery, and Psychiatry. 87
Francelle L, Galvan L, Gaillard MC, et al. (2015) The striatal long noncoding RNA Abhd11os is neuroprotective against an N-terminal fragment of mutant huntingtin in vivo. Neurobiology of Aging. 36: 1601.e7-16
Francelle L, Galvan L, Gaillard MC, et al. (2015) Loss of the thyroid hormone-binding protein Crym renders striatal neurons more vulnerable to mutant huntingtin in Huntington's disease. Human Molecular Genetics. 24: 1563-73
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