Laetitia Francelle

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Neurosciences
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"Laetitia Francelle"
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Parents

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Emmanuel Brouillet grad student 2011-2014
Vance Lemmon post-doc 2019-2019
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Publications

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Galvan L, Francelle L, Gaillard MC, et al. (2018) The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin. Brain : a Journal of Neurology
de Oliveira RM, Vicente Miranda H, Francelle L, et al. (2017) Correction: The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease. Plos Biology. 15: e1002601
de Oliveira RM, Vicente Miranda H, Francelle L, et al. (2017) The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease. Plos Biology. 15: e2000374
Francelle L, Lotz C, Outeiro T, et al. (2017) Contribution of Neuroepigenetics to Huntington's Disease. Frontiers in Human Neuroscience. 11: 17
Pépin J, Francelle L, Carrillo-de Sauvage MA, et al. (2016) In vivo imaging of brain glutamate defects in a knock-in mouse model of Huntington's disease. Neuroimage. 139: 53-64
Francelle L, Galvan L, Gaillard MC, et al. (2015) The striatal long noncoding RNA Abhd11os is neuroprotective against an N-terminal fragment of mutant huntingtin in vivo. Neurobiology of Aging. 36: 1601.e7-16
Francelle L, Galvan L, Gaillard MC, et al. (2015) Loss of the thyroid hormone-binding protein Crym renders striatal neurons more vulnerable to mutant huntingtin in Huntington's disease. Human Molecular Genetics. 24: 1563-73
Blum D, Herrera F, Francelle L, et al. (2015) Mutant huntingtin alters Tau phosphorylation and subcellular distribution. Human Molecular Genetics. 24: 76-85
Francelle L, Galvan L, Brouillet E. (2014) Possible involvement of self-defense mechanisms in the preferential vulnerability of the striatum in Huntington's disease. Frontiers in Cellular Neuroscience. 8: 295
Charbord J, Poydenot P, Bonnefond C, et al. (2013) High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes. Stem Cells (Dayton, Ohio). 31: 1816-28
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