Bruno M.D.C. Godinho
Affiliations: | University Of Massachusetts Med Sch Worcester |
Area:
RNA Therapeutics, siRNA, Oligonucleotide Delivery, CNSGoogle:
"Bruno Godinho"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| John F. Cryan | grad student | 2009-2014 | University College Cork, Ireland |
| Caitriona M. O'Driscoll | grad student | 2009-2014 | University College Cork |
| Anastasia Khvorova | post-doc | 2015-2019 | University Of Massachusetts Med Sch Worcester |
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Publications
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| Ferguson CM, Godinho BM, Alterman JF, et al. (2021) Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep. Jci Insight. 6 |
| Nikan M, Osborn MF, Coles AH, et al. (2017) Synthesis and Evaluation of Parenchymal Retention and Efficacy of a Metabolically Stable, O-phosphocholine-N-docosahexaenoyl-L-serine siRNA Conjugate in Mouse Brain. Bioconjugate Chemistry |
| Didiot MC, Hall LM, Coles AH, et al. (2016) Exosome-mediated Delivery of Hydrophobically Modified siRNA for Huntingtin mRNA Silencing. Molecular Therapy : the Journal of the American Society of Gene Therapy |
| Nikan M, Osborn MF, Coles AH, et al. (2016) Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain. Molecular Therapy. Nucleic Acids. 5: e344 |
| Coles AH, Osborn MF, Alterman JF, et al. (2015) A High-Throughput Method for Direct Detection of Therapeutic Oligonucleotide-Induced Gene Silencing In Vivo. Nucleic Acid Therapeutics |
| Malhotra M, Toulouse A, Godinho BM, et al. (2015) RNAi therapeutics for brain cancer: current advancements in RNAi delivery strategies. Molecular Biosystems |
| Gooding M, Malhotra M, McCarthy DJ, et al. (2015) Synthesis and characterization of rabies virus glycoprotein-tagged amphiphilic cyclodextrins for siRNA delivery in human glioblastoma cells: in vitro analysis. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 71: 80-92 |
| Godinho BM, Malhotra M, O'Driscoll CM, et al. (2015) Delivering a disease-modifying treatment for Huntington's disease. Drug Discovery Today. 20: 50-64 |
| Godinho BM, Ogier JR, Quinlan A, et al. (2014) PEGylated cyclodextrins as novel siRNA nanosystems: correlations between polyethylene glycol length and nanoparticle stability. International Journal of Pharmaceutics. 473: 105-12 |
| Godinho BM, McCarthy DJ, Torres-Fuentes C, et al. (2014) Differential nanotoxicological and neuroinflammatory liabilities of non-viral vectors for RNA interference in the central nervous system. Biomaterials. 35: 489-99 |