Mehdi Jorfi, Ph.D.

Affiliations: 
Neurology Harvard University, Cambridge, MA, United States 
Area:
Neurobiological Engineering, Alzheimer's disease
Website:
https://www.jorfilab.com/
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"Mehdi Jorfi"
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Parents

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Christoph Weder grad student 2011-2014 University of Fribourg (Chemistry Tree)
Paula T. Hammond post-doc (Chemistry Tree)
Rudolph E. Tanzi post-doc
Mehmet Toner post-doc (E-Tree)
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Publications

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Ning S, Jorfi M, Patel SR, et al. (2022) Neurotechnological Approaches to the Diagnosis and Treatment of Alzheimer's Disease. Frontiers in Neuroscience. 16: 854992
Lotlikar MS, Tarantino MB, Jorfi M, et al. (2022) Microfluidic separation of axonal and somal compartments of neural progenitor cells differentiated in a 3D matrix. Star Protocols. 3: 101028
Kim JJ, Jorfi M, Tanzi RE, et al. (2021) Patterning of interconnected human brain spheroids. Lab On a Chip
McAlpine CS, Park J, Griciuc A, et al. (2021) Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease. Nature
Bhattacharyya R, Black SE, Lotlikar MS, et al. (2021) Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes. Cell Reports. 35: 109134
von Maydell D, Jorfi M. (2021) A Synergistic Engineering Approach to Build Human Brain Spheroids. Methods in Molecular Biology (Clifton, N.J.). 2258: 151-169
von Maydell D, Jorfi M. (2019) The interplay between microglial states and major risk factors in Alzheimer's disease through the eyes of single-cell RNA-sequencing: beyond black and white. Journal of Neurophysiology
Ning S, Jorfi M. (2019) Beyond the sleep-amyloid interactions in Alzheimer's disease pathogenesis. Journal of Neurophysiology
DeVos SL, Corjuc BT, Commins C, et al. (2018) Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo. Brain : a Journal of Neurology
Jorfi M, D'Avanzo C, Tanzi RE, et al. (2018) Human Neurospheroid Arrays for In Vitro Studies of Alzheimer's Disease. Scientific Reports. 8: 2450
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