Tharaka Wijerathne, Ph.D

Affiliations: 
2020 Physiology Chungnam National Univ. S. Korea 
 2020-2024 Mechanobiology Western University of Health Sciences, Pomona, CA, United States 
Area:
Piezo channels, MscL Channels, TRPC channels, ORAI Channels, Slo3 channels, BK1 Channels, Hv1 Channels
Website:
https://www.researchgate.net/profile/Tharaka_Wijerathne
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"Tharaka Wijerathne"
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Publications

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Jiang W, Wijerathne TD, Zhang H, et al. (2023) Structural and thermodynamic framework for PIEZO1 modulation by small molecules. Proceedings of the National Academy of Sciences of the United States of America. 120: e2310933120
Cooray A, Chae MR, Wijerathne TD, et al. (2023) Hexane fraction of thunb. Seed extract enhances boar sperm motility via CatSper ion channel. Heliyon. 9: e13616
Wijerathne TD, Ozkan AD, Lacroix JJ. (2023) Microscopic mechanism of PIEZO1 activation by pressure-induced membrane stretch. The Journal of General Physiology. 155
Wijerathne T, Lin WY, Cooray A, et al. (2022) Hydrophobic interactions within the C terminus pole helices tunnel regulate calcium-dependent inactivation of TRPC3 in a calmodulin-dependent manner. Cell Calcium. 109: 102684
Wijerathne TD, Ozkan AD, Lacroix JJ. (2022) Yoda1's energetic footprint on Piezo1 channels and its modulation by voltage and temperature. Proceedings of the National Academy of Sciences of the United States of America. 119: e2202269119
Wijerathne TD, Ozkan AD, Lacroix JJ. (2021) Intermolecular Cooperative Gating in Piezo1 Channels Biophysical Journal. 120: 157a-158a
Wijerathne TD, Kim JH, Kim MJ, et al. (2019) Onion peel extract and its constituent, quercetin inhibits human Slo3 in a pH and calcium dependent manner. The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology. 23: 381-392
Kim KM, Wijerathne T, Hur JH, et al. (2018) Distinct gating mechanism of SOC channel involving STIM-Orai coupling and an intramolecular interaction of Orai in . Proceedings of the National Academy of Sciences of the United States of America
Kassahun Gebremeskel A, Wijerathne TD, Kim JH, et al. (2017) Psoralea corylifolia extract induces vasodilation in rat arteries through both endothelium-dependent and -independent mechanisms involving inhibition of TRPC3 channel activity and elaboration of prostaglandin. Pharmaceutical Biology. 55: 2136-2144
Wijerathne TD, Kim J, Yang D, et al. (2017) Intracellular calcium-dependent regulation of the sperm-specific calcium-activated potassium channel, hSlo3, by the BKCa activator LDD175. The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology. 21: 241-249
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