Derek Janssens

Affiliations: 
Fred Hutchinson Cancer Research Center, Seattle, WA, United States 
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"Derek Janssens"
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Janssens DH, Duran M, Otto DJ, et al. (2024) MLL oncoprotein levels influence leukemia lineage identities. Nature Communications. 15: 9341
Janssens DH, Greene JE, Wu SJ, et al. (2023) Scalable single-cell profiling of chromatin modifications with sciCUT&Tag. Nature Protocols
Meers MP, Llagas G, Janssens DH, et al. (2022) Multifactorial profiling of epigenetic landscapes at single-cell resolution using MulTI-Tag. Nature Biotechnology
Janssens DH, Otto DJ, Meers MP, et al. (2022) CUT&Tag2for1: a modified method for simultaneous profiling of the accessible and silenced regulome in single cells. Genome Biology. 23: 81
Thirmanne HN, Wu F, Janssens DH, et al. (2022) Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations. Elife. 11
Janssens DH, Meers MP, Wu SJ, et al. (2021) Automated CUT&Tag profiling of chromatin heterogeneity in mixed-lineage leukemia. Nature Genetics
Rives-Quinto N, Komori H, Ostgaard CM, et al. (2020) Sequential activation of transcriptional repressors promotes progenitor commitment by silencing stem cell identity genes. Elife. 9
Janssens DH, Wu SJ, Sarthy JF, et al. (2018) Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs. Epigenetics & Chromatin. 11: 74
Janssens DH, Hamm DC, Anhezini L, et al. (2017) An Hdac1/Rpd3-Poised Circuit Balances Continual Self-Renewal and Rapid Restriction of Developmental Potential during Asymmetric Stem Cell Division. Developmental Cell. 40: 367-380.e7
Janssens DH, Lee CY. (2014) It takes two to tango, a dance between the cells of origin and cancer stem cells in the Drosophila larval brain. Seminars in Cell & Developmental Biology. 28: 63-9
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