Sean P Moran
Affiliations: | Vanderbilt University, Nashville, TN |
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| Moran SP, Conn PJ. (2020) Leveraging bias to your advantage. Nature Chemical Biology. 16: 226-227 |
| Moran SP, Xiang Z, Doyle CA, et al. (2019) Biased M receptor-positive allosteric modulators reveal role of phospholipase D in M-dependent rodent cortical plasticity. Science Signaling. 12 |
| Moran SP, Maksymetz J, Conn PJ. (2019) Targeting Muscarinic Acetylcholine Receptors for the Treatment of Psychiatric and Neurological Disorders. Trends in Pharmacological Sciences. 40: 1006-1020 |
| Rook JM, Bertron JL, Cho HP, et al. (2018) A novel M1 PAM VU0486846 exerts efficacy in cognition models without displaying agonist activity or cholinergic toxicity. Acs Chemical Neuroscience |
| Moran SP, Cho HP, Maksymetz J, et al. (2018) PF-06827443 displays robust allosteric agonist and positive allosteric modulator activity in high receptor reserve and native systems. Acs Chemical Neuroscience |
| Moran SP, Dickerson JW, Cho HP, et al. (2018) M-positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology |
| Ghoshal A, Moran SP, Dickerson JW, et al. (2017) Role of mGlu5 receptors and inhibitory neurotransmission in M1 dependent muscarinic LTD in the prefrontal cortex: implications in schizophrenia. Acs Chemical Neuroscience |
| Maksymetz J, Moran SP, Conn PJ. (2017) Targeting metabotropic glutamate receptors for novel treatments of schizophrenia. Molecular Brain. 10: 15 |
| Grannan MD, Mielnik CA, Moran S, et al. (2016) Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction are Reversed by the Novel M1 PAM VU6004256. Acs Chemical Neuroscience |
| Raper J, Bosinger S, Johnson Z, et al. (2016) Increased irritability, anxiety, and immune reactivity in transgenic Huntington's disease monkeys. Brain, Behavior, and Immunity |