Krzysztof Jóźwiak
Affiliations: | Department of Biopharmacy | Medical University of Lublin |
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Sign in to add trainee| Piotr Drączkowski | grad student | Medical University of Lublin | |
| Karolina Pająk | grad student | Medical University of Lublin | |
| Anita Płazińska | grad student | Medical University of Lublin | |
| Ewelina Rutkowska | grad student | Medical University of Lublin | |
| Katarzyna Targowska-Duda | grad student | Medical University of Lublin | |
| Rafał Urniaż | grad student | Medical University of Lublin | |
| Artur Wnorowski | grad student | 2011-2015 | Medical University of Lublin |
| Anna Sroka-Bartnicka | post-doc | Medical University of Lublin | |
| Maciej Maj | research scientist | Medical University of Lublin |
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Publications
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| Plazinski W, Archala A, Jozwiak K, et al. (2024) Unraveling the Structural Basis of Biased Agonism in the β-Adrenergic Receptor Through Molecular Dynamics Simulations. Proteins |
| Malek R, Sałat K, Totoson P, et al. (2024) Discovery of New Highly Potent Histamine H Receptor Antagonists, Calcium Channel Blockers, and Acetylcholinesterase Inhibitors. Acs Chemical Neuroscience |
| Pachón-Angona I, Bernard PJ, Simakov A, et al. (2024) Design and Synthesis of Multi-Functional Ligands through Hantzsch Reaction: Targeting Ca Channels, Activating Nrf2 and Possessing Cathepsin S Inhibitory, and Antioxidant Properties. Pharmaceutics. 16 |
| Zaręba P, Łątka K, Mazur G, et al. (2023) Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, β-secretase, and amyloid β aggregation as potential treatment of Alzheimer's disease. European Journal of Medicinal Chemistry. 261: 115832 |
| Dakhlaoui I, Bernard PJ, Pietrzak D, et al. (2023) Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer's Disease Treatment. International Journal of Molecular Sciences. 24 |
| Maciag M, Plazinski W, Pulawski W, et al. (2023) A comprehensive pharmacological analysis of fenoterol and its derivatives to unravel the role of β-adrenergic receptor in zebrafish. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 160: 114355 |
| Malek R, Simakov A, Davis A, et al. (2022) Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation. Molecules (Basel, Switzerland). 28 |
| Wnorowski A, Dudzik D, Bernier M, et al. (2022) Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β adrenergic agonist. Scientific Reports. 12: 3618 |
| Pachón-Angona I, Maj M, Wnorowski A, et al. (2021) Synthesis of new Hantzsch adducts showing Ca channel blockade capacity, cholinesterase inhibition and antioxidant power. Future Medicinal Chemistry |
| Targowska-Duda KM, Budzynska B, Michalak A, et al. (2021) Type I and type II positive allosteric modulators of α7 nicotinic acetylcholine receptors induce antidepressant-like activity in mice by a mechanism involving receptor potentiation but not neurotransmitter reuptake inhibition. Correlation with mTOR intracellular pathway activation. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 52: 31-47 |