Stephen J Ryan

Doheny Eye Institute - UCLA 
"Stephen Ryan"

Steve Ryan devoted his life to pursuing the Doheny Eye Institute’s vision, “to further the conservation, improvement and restoration of human eyesight.” He served as President of the Doheny Eye Institute and helped guide Doheny to its place as a world class institution.

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Sreekumar PG, Spee C, Ryan SJ, et al. (2012) Mechanism of RPE cell death in α-crystallin deficient mice: a novel and critical role for MRP1-mediated GSH efflux. Plos One. 7: e33420
Xu J, Zhu D, Sonoda S, et al. (2012) Over-expression of BMP4 inhibits experimental choroidal neovascularization by modulating VEGF and MMP-9. Angiogenesis. 15: 213-27
Khankan R, Oliver N, He S, et al. (2011) Regulation of fibronectin-EDA through CTGF domain-specific interactions with TGFβ2 and its receptor TGFβRII. Investigative Ophthalmology & Visual Science. 52: 5068-78
Xu J, Zhu D, He S, et al. (2011) Transcriptional regulation of bone morphogenetic protein 4 by tumor necrosis factor and its relationship with age-related macular degeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2221-33
Sreekumar PG, Kannan R, Kitamura M, et al. (2010) αB crystallin is apically secreted within exosomes by polarized human retinal pigment epithelium and provides neuroprotection to adjacent cells. Plos One. 5: e12578
Zhou J, He S, Zhang N, et al. (2010) Neutrophils compromise retinal pigment epithelial barrier integrity. Journal of Biomedicine & Biotechnology. 2010: 289360
Kase S, He S, Sonoda S, et al. (2010) alphaB-crystallin regulation of angiogenesis by modulation of VEGF. Blood. 115: 3398-406
He S, Kumar SR, Zhou P, et al. (2010) Soluble EphB4 inhibition of PDGF-induced RPE migration in vitro. Investigative Ophthalmology & Visual Science. 51: 543-52
Sonoda S, Spee C, Barron E, et al. (2009) A protocol for the culture and differentiation of highly polarized human retinal pigment epithelial cells. Nature Protocols. 4: 662-73
Kim YH, He S, Kase S, et al. (2009) Regulated secretion of complement factor H by RPE and its role in RPE migration. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fã¼R Klinische Und Experimentelle Ophthalmologie. 247: 651-9
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