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Philip Kiser

Affiliations: 
Pharmacology Case Western Reserve University School of Medicine, Cleveland, OH, United States 
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Parents

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Krzysztof Palczewski grad student Case Western Medical School

Children

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Elliot H Choi grad student Case Western Medical School
Christopher Sander grad student 2016-2020 Case Western Medical School

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Publications

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Hong JD, Salom D, Choi EH, et al. (2024) Retinylidene Chromophore Hydrolysis from Mammalian Visual and Non-Visual Opsins. The Journal of Biological Chemistry. 105678
Wu A, Salom D, Hong JD, et al. (2023) Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain. Nature Communications. 14: 5209
Tworak A, Kolesnikov AV, Hong JD, et al. (2023) Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia. Cell Reports. 42: 112982
Bassetto M, Zaluski J, Li B, et al. (2023) Tuning the Metabolic Stability of Visual Cycle Modulators through Modification of an RPE65 Recognition Motif. Journal of Medicinal Chemistry
C Luu J, Saadane A, Leinonen H, et al. (2023) Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221045120
Hong JD, Salom D, Kochman MA, et al. (2022) Chromophore hydrolysis and release from photoactivated rhodopsin in native membranes. Proceedings of the National Academy of Sciences of the United States of America. 119: e2213911119
Huh CYL, Leinonen H, Nakayama T, et al. (2022) Retinoid therapy restores eye-specific cortical responses in adult mice with retinal degeneration. Current Biology : Cb
Occelli LM, Daruwalla A, De Silva SR, et al. (2021) A large animal model of RDH5-associated retinopathy recapitulates important features of the human phenotype. Human Molecular Genetics
Sander CL, Luu J, Kim K, et al. (2021) Structural evidence for visual arrestin priming via complexation of phosphoinositols. Structure (London, England : 1993)
Kiser PD. (2021) Retinal pigment epithelium 65 kDa protein (RPE65): An update. Progress in Retinal and Eye Research. 101013
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