Rona K. Graham
Affiliations: | 2000-2006 | Medical Genetics | University of British Columbia, Vancouver, Vancouver, BC, Canada |
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Parents
Sign in to add mentor| Michael R. Hayden | grad student | 2000-2006 | University of Sherbrooke (Canada) |
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Publications
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| Girling KD, Demers MJ, Laine J, et al. (2017) Activation of caspase-6 and cleavage of caspase-6 substrates is an early event in NMDA receptor-mediated excitotoxicity. Journal of Neuroscience Research |
| Riechers SP, Butland S, Deng Y, et al. (2016) Interactome network analysis identifies multiple caspase-6 interactors involved in the pathogenesis of HD. Human Molecular Genetics |
| Graham RK, Laroche M, Lessard-Beaudoin M, et al. (2016) B42 Early olfactory behaviour deficits associated with olfactory bulb atrophy and caspase-8 activation in HD rodent models Journal of Neurology, Neurosurgery & Psychiatry. 87: A24.1-A24 |
| Stroedicke M, Bounab Y, Strempel N, et al. (2015) Systematic interaction network filtering identifies CRMP1 as a novel suppressor of huntingtin misfolding and neurotoxicity. Genome Research. 25: 701-13 |
| Wong BK, Ehrnhoefer DE, Graham RK, et al. (2015) Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice. Neurobiology of Disease. 76: 24-36 |
| Butland SL, Sanders SS, Schmidt ME, et al. (2014) The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease. Human Molecular Genetics. 23: 4142-60 |
| Marco S, Giralt A, Petrovic MM, et al. (2013) Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models. Nature Medicine. 19: 1030-8 |
| Graham RK, Deng Y, Pouladi MA, et al. (2012) Caspase-6-Resistant Mutant Huntingtin Does not Rescue the Toxic Effects of Caspase-Cleavable Mutant Huntingtin in vivo. Journal of Huntington's Disease. 1: 243-60 |
| Pouladi MA, Brillaud E, Xie Y, et al. (2012) NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease. Neurobiology of Disease. 48: 282-9 |
| Uribe V, Wong BK, Graham RK, et al. (2012) Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice. Human Molecular Genetics. 21: 1954-67 |