Michael A Lodato, Ph.D.
Affiliations: | 2019- | Molecular, Cell, and Cancer Biology | University of Massachusetts Medical School, Worcester, MA, United States |
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Parents
Sign in to add mentor| Rudolf Jaenisch | grad student | 2007-2013 | MIT |
| Chris A. Walsh | post-doc | 2013-2019 | Children's Hospital Boston |
Collaborators
Sign in to add collaborator| Michael B. Miller | collaborator | 2017- | (Chemistry Tree) |
| Mollie Woodworth | collaborator | 2013-2016 | Children's Hospital Boston |
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Publications
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| Lai J, Demirbas D, Kim J, et al. (2023) ATM-deficiency-induced microglial activation promotes neurodegeneration in ataxia-telangiectasia. Cell Reports. 43: 113622 |
| Jeffries AM, Yu T, Ziegenfuss JS, et al. (2023) Single-cell transcriptomic and genomic changes in the aging human brain. Biorxiv : the Preprint Server For Biology |
| Kim SN, Viswanadham VV, Doan RN, et al. (2023) Cell lineage analysis with somatic mutations reveals late divergence of neuronal cell types and cortical areas in human cerebral cortex. Biorxiv : the Preprint Server For Biology |
| Lodato MA, Vijg J. (2023) Editorial: Somatic mutations, genome mosaicism and aging. Frontiers in Aging. 3: 1115408 |
| Lodato MA, Ziegenfuss JS. (2022) The two faces of DNA oxidation in genomic and functional mosaicism during aging in human neurons. Frontiers in Aging. 3: 991460 |
| Kim J, Huang AY, Johnson SL, et al. (2022) Prevalence and mechanisms of somatic deletions in single human neurons during normal aging and in DNA repair disorders. Nature Communications. 13: 5918 |
| Luquette LJ, Miller MB, Zhou Z, et al. (2022) Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements. Nature Genetics |
| Choudhury S, Huang AY, Kim J, et al. (2022) Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity. Nature Aging. 2: 714-725 |
| Bae T, Fasching L, Wang Y, et al. (2022) Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability. Science (New York, N.Y.). 377: 511-517 |
| Miller MB, Huang AY, Kim J, et al. (2022) Somatic genomic changes in single Alzheimer's disease neurons. Nature |