Andrew Kleist
Affiliations: | Duke University, Durham, NC |
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| Kleist AB, Jenjak S, Sente A, et al. (2022) Conformational selection guides β-arrestin recruitment at a biased G protein-coupled receptor. Science (New York, N.Y.). 377: 222-228 |
| Kleist AB, Peterson F, Tyler RC, et al. (2019) Solution NMR spectroscopy of GPCRs: Residue-specific labeling strategies with a focus on C-methyl methionine labeling of the atypical chemokine receptor ACKR3. Methods in Cell Biology. 149: 259-288 |
| Thomas MA, Kleist AB, Volkman BF. (2018) Decoding the chemotactic signal. Journal of Leukocyte Biology |
| Szpakowska M, Nevins AM, Meyrath M, et al. (2017) Different contribution of chemokine N-terminal features attest a different ligand binding mode and a bias towards activation of the atypical chemokine receptor ACKR3/CXCR7 compared to CXCR4 and CXCR3. British Journal of Pharmacology |
| Ziarek JJ, Kleist AB, London N, et al. (2017) Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation. Science Signaling. 10 |
| Kleist AB, Getschman AE, Ziarek JJ, et al. (2016) New paradigms in chemokine receptor signal transduction: moving beyond the two-site model. Biochemical Pharmacology |
| Strachan RT, Sun JP, Rominger DH, et al. (2014) Divergent transducer-specific molecular efficacies generate biased agonism at a G protein-coupled receptor (GPCR). The Journal of Biological Chemistry. 289: 14211-24 |
| Weiss DR, Ahn S, Sassano MF, et al. (2013) Conformation guides molecular efficacy in docking screens of activated β-2 adrenergic G protein coupled receptor. Acs Chemical Biology. 8: 1018-26 |