Meriem Semache
Affiliations: | Biochemistry and Molecular Medicine | Université de Montréal, Montréal, Canada |
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Publications
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Tummino TA, Iliopoulos-Tsoutsouvas C, Braz JM, et al. (2024) Large library docking for cannabinoid-1 receptor agonists with reduced side effects. Biorxiv : the Preprint Server For Biology |
Ehrlich AT, Semache M, Couvineau P, et al. (2021) Ackr3-Venus knock-in mouse lights up brain vasculature. Molecular Brain. 14: 151 |
Stepniewski TM, Mancini A, Ågren R, et al. (2021) Mechanistic insights into dopaminergic and serotonergic neurotransmission - concerted interactions with helices 5 and 6 drive the functional outcome. Chemical Science. 12: 10990-11003 |
Avet C, Sturino C, Grastilleur S, et al. (2020) The PAR2 inhibitor I-287 selectively targets Gα and Gα signaling and has anti-inflammatory effects. Communications Biology. 3: 719 |
Ehrlich AT, Semache M, Gross F, et al. (2019) Biased Signaling of the Mu Opioid Receptor Revealed in Native Neurons. Iscience. 14: 47-57 |
Ehrlich AT, Semache M, Bailly J, et al. (2017) Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing. Brain Structure & Function |
Semache M, Ghislain J, Zarrouki B, et al. (2014) Pancreatic and duodenal homeobox-1 nuclear localization is regulated by glucose in dispersed rat islets but not in insulin-secreting cell lines. Islets. 6: e982376 |
Semache M, Zarrouki B, Fontés G, et al. (2013) Per-Arnt-Sim kinase regulates pancreatic duodenal homeobox-1 protein stability via phosphorylation of glycogen synthase kinase 3β in pancreatic β-cells. The Journal of Biological Chemistry. 288: 24825-33 |
Amyot J, Semache M, Ferdaoussi M, et al. (2012) Lipopolysaccharides impair insulin gene expression in isolated islets of Langerhans via Toll-Like Receptor-4 and NF-κB signalling. Plos One. 7: e36200 |
Semplici F, Vaxillaire M, Fogarty S, et al. (2011) Human mutation within Per-Arnt-Sim (PAS) domain-containing protein kinase (PASK) causes basal insulin hypersecretion. The Journal of Biological Chemistry. 286: 44005-14 |