Shane Wright
Affiliations: | Biochemistry and Molecular Medicine | Université de Montréal, Montréal, Canada |
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Wright SC, Motso A, Koutsilieri S, et al. (2023) GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics. Nature Communications. 14: 6243 |
Xu L, Chen B, Schihada H, et al. (2021) Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric G. Cell Research |
Wright SC, Bouvier M. (2021) Illuminating the complexity of GPCR pathway selectivity - advances in biosensor development. Current Opinion in Structural Biology. 69: 142-149 |
Wright SC, Lukasheva V, Le Gouill C, et al. (2021) BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated G activation at early endosomes. Proceedings of the National Academy of Sciences of the United States of America. 118 |
Sundqvist M, Holdfeldt A, Wright SC, et al. (2020) Barbadin selectively modulates FPR2-mediated neutrophil functions independent of receptor endocytosis. Biochimica Et Biophysica Acta. Molecular Cell Research. 118849 |
Okashah N, Wright SC, Kawakami K, et al. (2020) Agonist-induced formation of unproductive receptor-G complexes. Proceedings of the National Academy of Sciences of the United States of America |
Wright SC, Kozielewicz P, Kowalski-Jahn M, et al. (2019) A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection. Nature Communications. 10: 667 |
Arthofer E, Dijksterhuis J, Hot B, et al. (2019) Class Frizzled GPCRs (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019 |
Wright SC, Cañizal MCA, Benkel T, et al. (2018) FZD is a Gα-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs. Science Signaling. 11 |
Schulte G, Wright SC. (2018) Frizzleds as GPCRs - More Conventional Than We Thought! Trends in Pharmacological Sciences |