Jennifer L. Hope

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Immunology
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"Jennifer Hope"
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Hope JL, Otero DC, Bae EA, et al. (2023) PSGL-1 attenuates early TCR signaling to suppress CD8 T cell progenitor differentiation and elicit terminal CD8 T cell exhaustion. Cell Reports. 42: 112436
Dolina JS, Lee J, Moore EL, et al. (2022) Developmentally distinct CD4 T lineages shape the CD8 T cell response to acute infection. Proceedings of the National Academy of Sciences of the United States of America. 119: e2113329119
Hope JL, Zhao M, Stairiker CJ, et al. (2022) MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8 T Cell Responses. Journal of Immunology (Baltimore, Md. : 1950). 208: 603-617
Hope JL, Bradley LM. (2021) Lessons in antiviral immunity. Science (New York, N.Y.). 371: 464-465
Shen JZ, Qiu Z, Wu Q, et al. (2020) FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells. Cell
Zhao M, Kiernan CH, Stairiker CJ, et al. (2020) Rapid in vitro generation of bona fide exhausted CD8+ T cells is accompanied by Tcf7 promotor methylation. Plos Pathogens. 16: e1008555
Hope JL, Spantidea PI, Kiernan CH, et al. (2019) Microenvironment-Dependent Gradient of CTL Exhaustion in the AE17sOVA Murine Mesothelioma Tumor Model. Frontiers in Immunology. 10: 3074
Hope JL, Stairiker CJ, Bae EA, et al. (2019) Striking a Balance-Cellular and Molecular Drivers of Memory T Cell Development and Responses to Chronic Stimulation. Frontiers in Immunology. 10: 1595
Stelekati E, Chen Z, Manne S, et al. (2018) Long-Term Persistence of Exhausted CD8 T Cells in Chronic Infection Is Regulated by MicroRNA-155. Cell Reports. 23: 2142-2156
Hope JL, Stairiker CJ, Spantidea PI, et al. (2017) The Transcription Factor T-Bet Is Regulated by MicroRNA-155 in Murine Anti-Viral CD8+ T Cells via SHIP-1. Frontiers in Immunology. 8: 1696
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