Neelam Shahani, Ph.D.

Neuroscience Scripps Florida, Jupiter, FL, United States 
Modulators of neurodegenerative disease relevant biochemical pathways.
"Neelam Shahani"

Ph.D., National Institute of Mental Health & Neuro Sciences (NIMHANS), Bangalore, India 2000

Mean distance: 15.99 (cluster 11)
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Ramírez-Jarquín UN, Shahani N, Pryor W, et al. (2020) The mammalian target of rapamycin (mTOR) kinase mediates haloperidol-induced cataleptic behavior. Translational Psychiatry. 10: 336
Sharma M, Rajendrarao S, Shahani N, et al. (2020) Cyclic GMP-AMP synthase promotes the inflammatory and autophagy responses in Huntington disease. Proceedings of the National Academy of Sciences of the United States of America
Eshraghi M, Ramírez-Jarquín UN, Shahani N, et al. (2020) RasGRP1 is a causal factor in the development of l-DOPA-induced dyskinesia in Parkinson's disease. Science Advances. 6: eaaz7001
Sharma M, Jarquín UNR, Rivera O, et al. (2019) Rhes, a striatal-enriched protein, promotes mitophagy via Nix. Proceedings of the National Academy of Sciences of the United States of America
Shahani N, Huang WC, Varnum M, et al. (2016) Forebrain depletion of Rheb GTPase elicits spatial memory deficits in mice. Neurobiology of Aging. 50: 134-143
Shahani N, Swarnkar S, Giovinazzo V, et al. (2016) RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum. Science Signaling. 9: ra111
Kim SH, Shahani N, Bae BI, et al. (2016) Allele-specific regulation of mutant Huntingtin by Wig1, a downstream target of p53. Human Molecular Genetics
Swarnkar S, Chen Y, Pryor WM, et al. (2015) Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease. Neurobiology of Disease. 82: 66-77
Nakajima H, Kubo T, Ihara H, et al. (2015) Nuclear-translocated Glyceraldehyde-3-phosphate Dehydrogenase Promotes Poly(ADP-ribose) Polymerase-1 Activation during Oxidative/Nitrosative Stress in Stroke. The Journal of Biological Chemistry. 290: 14493-503
Tyagi R, Shahani N, Gorgen L, et al. (2015) Rheb Inhibits Protein Synthesis by Activating the PERK-eIF2α Signaling Cascade. Cell Reports
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