joseph r. moskal, Ph.D.

Affiliations: 
Biomedical Engineering Northwestern University, Evanston, IL 
Area:
Pharmacogenomics, Drug Discovery, Brain Tumor Therapeutics
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"joseph moskal"
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Publications

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Burgdorf J, Brudzynski S, Moskal J. (2020) Using rat ultrasonic vocalization to study the neurobiology of emotion: from basic science to the development of novel therapeutics for affective disorders. Current Opinion in Neurobiology. 60: 192-200
Burgdorf JS, Christian EP, Sørensen L, et al. (2019) A translational EEG-based approach to assess modulation of long-lasting NMDAR-dependent synaptic plasticity. Psychopharmacology
Bowers MS, Cacheaux LP, Sahu SU, et al. (2019) NYX-2925 induces metabotropic NMDAR signaling that enhances synaptic NMDAR and AMPAR. Journal of Neurochemistry
Donello JE, Banerjee P, Li YX, et al. (2018) Positive N-Methyl-D-Aspartate Receptor Modulation by Rapastinel Promotes Rapid and Sustained Antidepressant-like Effects. The International Journal of Neuropsychopharmacology
Ghoreishi-Haack N, Priebe JM, Aguado JD, et al. (2018) NYX-2925 is a novel NNMDA receptor modulator that induces rapid and long-lasting analgesia in rat models of neuropathic pain. The Journal of Pharmacology and Experimental Therapeutics
Khan MA, Houck DR, Gross AL, et al. (2017) NYX-2925 is a novel NMDA receptor-specific spirocyclic-β-lactam that modulates synaptic plasticity processes associated with learning and memory. The International Journal of Neuropsychopharmacology
Liu RJ, Duman C, Kato T, et al. (2016) GLYX-13 Produces Rapid Antidepressant Responses with Key Synaptic and Behavioral Effects Distinct from Ketamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Moskal JR, Burgdorf JS, Stanton PK, et al. (2016) The Development of Rapastinel (Formerly GLYX-13); a rapid acting and long lasting antidepressant. Current Neuropharmacology
Burgdorf J, Zhang XL, Weiss C, et al. (2015) The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus. Neuroscience. 308: 202-211
Zhang XL, Shuttleworth CW, Moskal JR, et al. (2015) Suppression of spreading depolarization and stabilization of dendritic spines by GLYX-13, an NMDA receptor glycine-site functional partial agonist. Experimental Neurology. 273: 312-321
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