Leonid Tyan, PhD
Affiliations: | 2020- | Pediatrics | Yale University, New Haven, CT |
Area:
physiology, electrophysiologyGoogle:
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Publications
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Tyan L, Turner D, Komp KR, et al. (2021) Caveolin-3 is required for regulation of transient outward potassium current by angiotensin II in mouse atrial myocytes. American Journal of Physiology. Heart and Circulatory Physiology |
Asfaw TN, Tyan L, Glukhov A, et al. (2020) A Compartmentalized Mathematical Model of Mouse Atrial Myocytes. American Journal of Physiology. Heart and Circulatory Physiology |
Lang D, ratajczyk L, Tyan L, et al. (2020) Abstract 418: Caveolar Disruption of L-type Calcium Channel and Ryanodine Receptor Facilitates Atrial Ectopy and Arrhythmogenesis in Heart Failure Mice Circulation Research. 127 |
Laforest B, Dai W, Tyan L, et al. (2019) Atrial fibrillation risk loci interact to modulate Ca2+-dependent atrial rhythm homeostasis. The Journal of Clinical Investigation |
Egorov YV, Lang D, Tyan L, et al. (2019) Caveolae-Mediated Activation of Mechanosensitive Chloride Channels in Pulmonary Veins Triggers Atrial Arrhythmogenesis. Journal of the American Heart Association. 8: e012748 |
Dai W, Laforest B, Tyan L, et al. (2019) A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice. Elife. 8 |
Dai W, Laforest B, Tyan L, et al. (2019) Author response: A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice Elife |
Piro ZD, Lodin R, Tyan L, et al. (2019) Region-Specific Stretch-Induced Disruption of Caveolae Decreases Expression of Mechanosensitive Chloride Channels and Stimulates Fibrogenesis Promoting Arrhythmogenic Atrial Ectopy in Failing Mice Biophysical Journal. 116 |
Lang D, Tyan L, Warden A, et al. (2019) Disruption of Caveolar Microdomains Creates “Hot Spots” for Atrial Ectopy and Arrythmogenesis in Heart Failure Mice Biophysical Journal. 116 |
Tyan L, Foell JD, Vincent KP, et al. (2018) Long QT syndrome caveolin-3 mutations differentially modulate K 4 and Ca 1.2 channels to contribute to action potential prolongation. The Journal of Physiology |