Show-Ling Shyng

Oregon Health and Science University, Portland, OR 
KATP channels
"Show-Ling Shyng"
Mean distance: 17.47 (cluster 11)
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Boodhansingh KE, Kandasamy B, Mitteer L, et al. (2019) Novel dominant K channel mutations in infants with congenital hyperinsulinism: Validation by in vitro expression studies and in vivo carrier phenotyping. American Journal of Medical Genetics. Part A
Martin GM, Rex EA, Devaraneni P, et al. (2016) Pharmacological Correction of Trafficking Defects in ATP-Sensitive Potassium Channels Caused by Sulfonylurea Receptor 1 Mutations. The Journal of Biological Chemistry
Wu Y, Shyng SL, Chen PC. (2015) Concerted Trafficking Regulation of Kv2.1 and KATP Channels by Leptin in Pancreatic β-cells. The Journal of Biological Chemistry
Devaraneni PK, Martin GM, Olson EM, et al. (2015) Structurally distinct ligands rescue biogenesis defects of the KATP channel complex via a converging mechanism. The Journal of Biological Chemistry. 290: 7980-91
Saint-Martin C, Zhou Q, Martin GM, et al. (2015) Monoallelic ABCC8 mutations are a common cause of diazoxide-unresponsive diffuse form of congenital hyperinsulinism. Clinical Genetics. 87: 448-54
Xie L, Liang T, Kang Y, et al. (2014) Phosphatidylinositol 4,5-biphosphate (PIP2) modulates syntaxin-1A binding to sulfonylurea receptor 2A to regulate cardiac ATP-sensitive potassium (KATP) channels. Journal of Molecular and Cellular Cardiology. 75: 100-10
Zhou Q, Chen PC, Devaraneni PK, et al. (2014) Carbamazepine inhibits ATP-sensitive potassium channel activity by disrupting channel response to MgADP. Channels (Austin, Tex.). 8: 376-82
Martin GM, Chen PC, Devaraneni P, et al. (2013) Pharmacological rescue of trafficking-impaired ATP-sensitive potassium channels. Frontiers in Physiology. 4: 386
Chen PC, Kryukova YN, Shyng SL. (2013) Leptin regulates KATP channel trafficking in pancreatic β-cells by a signaling mechanism involving AMP-activated protein kinase (AMPK) and cAMP-dependent protein kinase (PKA). The Journal of Biological Chemistry. 288: 34098-109
Chen PC, Olson EM, Zhou Q, et al. (2013) Carbamazepine as a novel small molecule corrector of trafficking-impaired ATP-sensitive potassium channels identified in congenital hyperinsulinism. The Journal of Biological Chemistry. 288: 20942-54
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