Harry V. Gelboin
Affiliations: | Molecular Carcinogenesis | National Cancer Institute, Rockville, MD, United States |
Area:
cytochrome P450 metabolism of carcinogens and drugsWebsite:
http://dx.doi.org/10.1093/carcin/bgq093Google:
"Harry V. Gelboin"Bio:
(1929 - 2010)
http://home.ccr.cancer.gov/metabolism/hvgccr.htm
http://www3.cancer.gov/intra/lmc/hvg.htm
http://carcin.oxfordjournals.org/content/31/7/1308.full.pdf
Mean distance: 9.99 | S | N | B | C | P |
Parents
Sign in to add mentor| James A. Miller | grad student | 1958 | UW Madison | |
| (In vivo and in vitro studies on the formation of protein-bound derivatives of aminoazo dyes by rat liver) | ||||
| Elizabeth Cavert Miller | grad student | 1958 | UW Madison | |
| Giulio L. Cantoni | post-doc | 1958-1961 | NIH | |
| Louis Sokoloff | post-doc | 1958-1961 | NIMH | |
Children
Sign in to add trainee| Lawrence A. Loeb | research assistant | 1962-1964 | National Cancer Institute |
| James P. Whitlock, Jr. | grad student | 1975 | NIH (Neurotree) |
BETA: Related publications
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Publications
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| Chou YC, Chung YT, Liu TY, et al. (2010) The oxidative metabolism of dimemorfan by human cytochrome p450 enzymes Journal of Pharmaceutical Sciences. 99: 1063-1077 |
| Elovaara E, Stockmann-Juvala H, Mikkola J, et al. (2007) Interactive effects of methyl tertiary-butyl ether (MTBE) and tertiary-amyl methyl ether (TAME), ethanol and some drugs: Triglyceridemia, liver toxicity and induction of CYP (2E1, 2B1) and phase II enzymes in female Wistar rats. Environmental Toxicology and Pharmacology. 23: 64-72 |
| Gelboin HV, Krausz K. (2006) Monoclonal antibodies and multifunctional cytochrome P450: Drug metabolism as paradigm Journal of Clinical Pharmacology. 46: 353-372 |
| Aleksa K, Matsell D, Krausz K, et al. (2005) Cytochrome P450 3A and 2B6 in the developing kidney: implications for ifosfamide nephrotoxicity. Pediatric Nephrology (Berlin, Germany). 20: 872-85 |
| Ufer M, Svensson JO, Krausz KW, et al. (2004) Identification of cytochromes P450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro European Journal of Clinical Pharmacology. 60: 173-182 |
| Hu Y, Krausz K, Gelboin HV, et al. (2004) CYP2C subfamily, primarily CYP2C9, catalyses the enantioselective demethylation of the endocrine disruptor pesticide methoxychlor in human liver microsomes: Use of inhibitory monoclonal antibodies in P450 identification Xenobiotica. 34: 117-132 |
| Granvil CP, Krausz KW, Gelboin HV, et al. (2002) 4-Hydroxylation of debrisoquine by human CYP1A1 and its inhibition by quinidine and quinine Journal of Pharmacology and Experimental Therapeutics. 301: 1025-1032 |
| Friedman FK, Park SS, Fujino T, et al. (2001) Phenotyping cytochromes P450 with monoclonal antibodies. Toxicologic Pathology. 12: 155-61 |
| Niemelä O, Parkkila S, Juvonen RO, et al. (2000) Cytochromes P450 2A6, 2E1, and 3A and production of protein-aldehyde adducts in the liver of patients with alcoholic and non-alcoholic liver diseases Journal of Hepatology. 33: 893-901 |
| Krausz KW, Goldfarb I, Yang TJ, et al. (2000) An inhibitory monoclonal antibody to human cytochrome P450 that specifically binds and inhibits P4502C9II, an allelic variant of P4502C9 having a single amino acid change Arg144 Cys Xenobiotica. 30: 619-625 |